Browse our latest Neuroscience articles

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    1. Neuroscience

    Clonally related, Notch-differentiated spinal neurons integrate into distinct circuits

    Saul Bello-Rojas, Martha W Bagnall
    Pairs of spinal cord neurons arising from a shared progenitor get input from and make outputs to mostly different synaptic partners.
    1. Computational and Systems Biology
    2. Neuroscience

    Emergent color categorization in a neural network trained for object recognition

    Jelmer P de Vries, Arash Akbarinia ... Karl R Gegenfurtner
    Human-like color categories emerge in a Deep Neural Network trained only on object recognition.
    1. Neuroscience

    Retinoic acid-gated BDNF synthesis in neuronal dendrites drives presynaptic homeostatic plasticity

    Shruti Thapliyal, Kristin L Arendt ... Lu Chen
    Synaptic silencing-induced homeostatic enhancement of presynaptic glutamate release is mediated by the postsynaptic retinoic acid-dependent brain-derived neurotrophic factor (BDNF) synthesis from dendritically targeted BDNF transcripts, leading to retrograde activation of presynaptic tropomyosin receptor kinase B receptors.
    1. Neuroscience

    Ultrastructural effects of sleep and wake on the parallel fiber synapses of the cerebellum

    Sophia S Loschky, Giovanna Maria Spano ... Chiara Cirelli
    In the mouse cerebellum, the number of branched synapses is reduced in half after sleep compared to after wake.
    1. Neuroscience

    Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal sensitive period

    Sarah E Canetta, Emma S Holt ... Christoph Kellendonk
    Prefrontal PV interneuron activity during development is necessary for prefrontal circuit maturation, supporting adult prefrontal network function and cognitive flexibility.
    1. Cell Biology
    2. Neuroscience

    The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila

    Arnau Llobet Rosell, Maria Paglione ... Lukas Jakob Neukomm
    Levels of the metabolite NMN, the precursor of NAD+, determine whether dSarm-mediated axon death signaling is activated and injury-induced axon degeneration executed in the fruit fly Drosophila.
    1. Neuroscience

    Feedback inhibition underlies new computational functions of cerebellar interneurons

    Hunter E Halverson, Jinsook Kim ... George J Augustine
    An inhibitory feedback circuit from Purkinje cells to molecular layer interneurons within the cerebellum has been characterized and found to be employed in vivo during motor learning.
    1. Neuroscience

    Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice

    Eva M Szego, Laura Malz ... Hella Luksch
    Constitutive activation of an innate immunity response in mouse brain causes degeneration of dopaminergic neurons, suggesting novel targets for potentially neuroprotective strategies.
    1. Evolutionary Biology
    2. Neuroscience

    Neurovascular anatomy of dwarf dinosaur implies precociality in sauropods

    Marco Schade, Nils Knötschke ... Sebastian Stumpf
    Computed tomography data reveal large and adult-looking inner ears in very young individuals of the long-necked dinosaur Europasaurus holgeri suggesting precociality in this dwarfed island dweller from the Late Jurassic of Germany.
    1. Neuroscience

    Scratch-AID, a deep learning-based system for automatic detection of mouse scratching behavior with high accuracy

    Huasheng Yu, Jingwei Xiong ... Wenqin Luo
    Scratch-AID, a deep learning-based system for automatic quantification of mouse scratching behavior, could replace labor-intensive manual quantification and facilitate high through-put anti-itch drug screening.