Andres De La Rossa, Marine H Laporte ... Jean-Claude Martinou
Glutamatergic neurons lacking the mitochondrial pyruvate carrier show reduced M-type potassium channel activity and hyperexcitability upon intense firing.
Major neuronal subtypes in M1 show differential responses to reward and reward-associated stimuli and undergo cell-type-specific plasticity following associative learning.
Mitchell Bishop, Maximilian Weinhold ... Shahriar SheikhBahaei
The introduced Python tool was used to characterize breathing behaviors of common marmosets in room air and acute hypoxic (10% O2) and hypercapnic (6% CO2) conditions.
Ten-fold Robust Expansion Microscopy (TREx) is a new method for 10-fold physical expansion of specimens in one round of gel embedding, enabling nanoscale imaging of antibody stains and ultrastructural detail.
Akis Stavropoulos, Kaushik J Lakshminarasimhan ... Dora E Angelaki
Human path integration accuracy is strongly influenced by the underlying control dynamics, but less so when visual, rather than vestibular, feedback is available.
Han-Xiong Bear Zhang, Laurel Heckman ... Bruce P Bean
The phytocannabinoid cannabidiol, an antiepileptic agent whose molecular targets are unclear, was found to potently enhance current carried by cloned human Kv7.2/7.3 channels and native M-current in mouse and rat neurons.
Sergio Velasco-Aviles, Nikiben Patel ... Hugo Cabedo
Myelin generation during development and nerve regeneration is guaranteed by responsive backup circuits that coordinate class IIa HDACs to repress the expression of negative regulators of myelination and permit Schwann cell differentiation in response to cAMP.
Mohit Dubey, Maria Pascual-Garcia ... Maarten HP Kole
Demyelination disrupts fast inhibition of pyramidal neurons, thereby changing neocortical rhythms and causing the emergence of brief epileptic-like discharges.