Browse our latest Neuroscience articles

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    1. Developmental Biology
    2. Neuroscience

    Electrical synaptic transmission requires a postsynaptic scaffolding protein

    Abagael M Lasseigne, Fabio A Echeverry ... Adam C Miller
    A postsynaptic, intracellular, scaffolding protein is necessary to build neuronal gap junctions, revealing an unanticipated complexity of molecular and functional organization of electrical synapses.
    1. Neuroscience

    Visualizing anatomically registered data with brainrender

    Federico Claudi, Adam L Tyson ... Tiago Branco
    Brainrender is an open-source and user-friendly software for combining any type of anatomically registered data into custom interactive 3D renderings.
    1. Neuroscience

    Rapid recycling of glutamate transporters on the astroglial surface

    Piotr Michaluk, Janosch Peter Heller, Dmitri A Rusakov
    Rapid membrane turnover is the main 'redeployment' route for the immobile fraction of surface-expressed astroglial glutamate transporters that confine excitatory transmission to the synaptic cleft.
    1. Cell Biology
    2. Neuroscience

    Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior

    Stephan Raiders, Erik Calvin Black ... Aakanksha Singhvi
    A peripheral sense-organ glia actively engulfs fragments of a sensory neuron ending to modify neuron shape and associated animal sensory behavior in Caenorhabditis elegans..
    1. Neuroscience

    Neural effects of propofol-induced unconsciousness and its reversal using thalamic stimulation

    André M Bastos, Jacob A Donoghue ... Earl K Miller
    Understanding how general anesthesia changes neural dynamics in the cortex and thalamus can lead to its safer use and shed light on the nature of consciousness.
    1. Medicine
    2. Neuroscience

    The mechanism underlying transient weakness in myotonia congenita

    Jessica H Myers, Kirsten Denman ... Mark M Rich
    Transient weakness in myotonia congenita is caused by depolarization secondary to activation of persistent Na+ current in skeletal muscle.
    1. Neuroscience

    An open-source device for measuring food intake and operant behavior in rodent home-cages

    Bridget A Matikainen-Ankney, Thomas Earnest ... Alexxai V Kravitz
    An open-source behavioral platform allows for operant, feeding, and circadian experiments in rodent home-cages.
    1. Developmental Biology
    2. Neuroscience

    MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs

    Shih-Hsin Chang, Yi-Ching Su ... Jun-An Chen
    The miR-34/449 family is abundantly expressed in the central nervous system, and fine-tunes optimal numbers of spinal interneurons to ensure sensory-motor circuit outputs.
    1. Neuroscience

    Spontaneous and evoked activity patterns diverge over development

    Lilach Avitan, Zac Pujic ... Geoffrey J Goodhill
    Spontaneous and evoked patterns of neural activity in the larval zebrafish tectum become less similar over development, in contrast with a previous hypothesis for the computational role of spontaneous activity.
    1. Ecology
    2. Neuroscience

    Probing the decision-making mechanisms underlying choice between drug and nondrug rewards in rats

    Youna Vandaele, Magalie Lenoir ... Serge H Ahmed
    In a drug choice setting, rats’ preference is initially driven by deliberative processes but shifts to more automatic selection processes after extended training, in accordance with the sequential choice model.