Group III metabotropic glutamate receptor inhibition facilitates synaptic plasticity in the plasticity-resistant synapses of hippocampal area CA2, a brain region critical for social memory.
Combining psychophysics and functional MRI reveals a qualitative asymmetry in neural engagement when reflecting on whether a stimulus is seen (detection) compared to reflecting on what a stimulus is (discrimination).
Jérôme Dockès, Russell A Poldrack ... Gaël Varoquaux
Full-text analysis of the human brain-imaging literature can predict the spatial distribution of observations in the brain given the description of a subject of study.
The work uncovers a muscle-epidermis-glia signaling axis, modulated by protease mig-17 and the basement membrane, that regulates synaptic allometry during growth in Caenorhabditis elegans.
Stephen M Smith, Lloyd T Elliott ... Karla L Miller
Imaging of structure and function in the brain from thousands of participants was used along with genetics and biophysical measures to study many different aspects of how the brain ages.
Zaixu Cui, Jennifer Stiso ... Theodore D Satterthwaite
Structural network topology develops during adolescence to facilitate activation of the fronto-parietal executive system with lower theoretical energetic cost.
Computational analyses quantitatively account for optical refraction at air-water interfaces to enable visual neuroscientists to present distortion-free stimuli to underwater animals.
Cathryn R Cadwell, Federico Scala ... Andreas Savas Tolias
Excitatory cortical neurons with a shared developmental lineage are transcriptomically diverse and preferentially connect to each other vertically, across cortical layers, but not laterally within the same layer.
Joshua Henk Balsters, Valerio Zerbi ... Rogier B Mars
Connectivity fingerprint matching bridges the gap between mouse and primate neuroanatomy, addressing crucial questions surrounding brain evolution that likely impact translation across species.
