Browse our latest Neuroscience articles

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    1. Neuroscience

    Feeding state functionally reconfigures a sensory circuit to drive thermosensory behavioral plasticity

    Asuka Takeishi, Jihye Yeon ... Piali Sengupta
    Starvation modulates thermotaxis behaviors in C. elegans via functional reconfiguration of a sensory network by gut-brain signaling.
    1. Neuroscience

    Variation of connectivity across exemplar sensory and associative thalamocortical loops in the mouse

    Arghya Mukherjee, Navdeep Bajwa ... Michael M Halassa
    Compared to a sensory thalamocortical circuit, the mediodorsal thalamus preferentially innervates prefrontal cortical interneurons, and enhancing excitability of this thalamic structure drives prefrontal activity patterns that are dominated by inhibition.
    1. Neuroscience

    Functional links between sensory representations, choice activity, and sensorimotor associations in parietal cortex

    Ting-Yu Chang, Raymond Doudlah ... Ari Rosenberg
    The fidelity of 3D visual object representations, choice-related activity, and experience-dependent sensorimotor associations are functionally linked in the caudal intraparietal area.
    1. Neuroscience

    Rapid computations of spectrotemporal prediction error support perception of degraded speech

    Ediz Sohoglu, Matthew H Davis
    Analysis of speech acoustics and human brain activity reveals the neural computations by which listeners combine speech input with prior expectations.
    1. Neuroscience

    Hippocampal inputs engage CCK+ interneurons to mediate endocannabinoid-modulated feed-forward inhibition in the prefrontal cortex

    Xingchen Liu, Jordane Dimidschstein ... Adam G Carter
    Endocannabinoids modulate ventral hippocampal inputs to the infralimbic prefrontal cortex by dampening feed-forward inhibition mediated by cholecystokinin-expressing (CCK+) interneurons onto layer 5 intratelencephalic (IT) cells.
    1. Neuroscience

    Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations

    Chuyu Chen, Giulia Soto ... Loukia Parisiadou
    Although human Parkinson's disease is linked to dopamine loss, two distinct mutations in a kinase associated with familial Parkinson's operate downstream, altering excitatory synapses on dopamine-sensing neurons.
    1. Neuroscience

    Modulation of sleep-courtship balance by nutritional status in Drosophila

    José M Duhart, Victoria Baccini ... Kyunghee Koh
    The sleep-courtship balance in Drosophila males is modulated by yeast/protein availability, and dopaminergic neurons projecting to the protocerebral bridge act downstream of courtship-regulating neurons for male sleep regulation.
    1. Neuroscience

    Entorhinal-retrosplenial circuits for allocentric-egocentric transformation of boundary coding

    Joeri BG van Wijngaarden, Susanne S Babl, Hiroshi T Ito
    An extended border coding circuit across the entorhinal and retrosplenial cortex incorporates self-referenced and viewpoint-invariant boundary information to guide navigation behavior.
    1. Developmental Biology
    2. Neuroscience

    Direct glia-to-neuron transdifferentiation gives rise to a pair of male-specific neurons that ensure nimble male mating

    Laura Molina-García, Carla Lloret-Fernández ... Richard J Poole
    A novel developmental mechanism generates a previously undescribed pair of sex-specific proprioceptive neurons required for male-specific behaviour.
    1. Neuroscience
    2. Physics of Living Systems

    Walking Drosophila navigate complex plumes using stochastic decisions biased by the timing of odor encounters

    Mahmut Demir, Nirag Kadakia ... Thierry Emonet
    Visualized odor encounters show that Drosophila navigate spatiotemporally complex odor plumes using random walks biased by the timing of brief and unpredictable odor encounters.