Federico Miguez-Cabello, Nuria Sánchez-Fernández ... David Soto
A variable number of auxiliary subunit molecules (TARPs) accompanying AMPARs have a differential impact on channel behavior showing also striking differences between AMPAR subtypes.
Ramesh Chittajallu, Kurt Auville ... Chris J McBain
Similar to their mouse counterparts, human neurogliaform cells that comprise a specialized from of inhibitory neuron, possess the ability to modulate their intrinsic excitability in response to ongoing network activity.
Replay of recently experienced trajectories during a decision task is coupled with more effective adaptation to change, whereas replay during rest is associated with limited decision making flexibility.
The composition of inhibitory and excitatory synaptic inputs to the apical dendrites of pyramidal cells in mouse cortex is specific to the type of pyramidal cells.
Neural stem cells in the dentate gyrus have unique cytoplasmic processes that promote privileged access to circulating factors by a unique contact point with an endothelial cell.
Kirby M Donnelly, Olivia R DeLorenzo ... Margaret M Panning Pearce
Prion-like transfer of mutant huntingtin aggregates from presynaptic to postsynaptic neurons is enhanced by neuronal silencing and requires passage through the cytoplasm of Draper-expressing phagocytic glia in adult Drosophila brains.
The overactivation of noradrenergic inputs to the amygdala during severe fear learning increases memory stability at the expense of lability, rendering the trace resistant to memory destabilization and reconsolidation.
Taste-dependent satiation, which induces proper cessation of feeding in mammals as well as insects, is weakened by sugar-diet-driven taste impairment in the fruit fly.
The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.