Sonic hedgehog signaling is crucial for the self-renewal of outer radial glial cells and gyrus formation of the cerebral cortex in gyrencephalic mammals.
Sex-specific characteristics of the fruit fly courtship behavior are not specified by a single binary switch, but as a combination of traits that are modularly specified by separable genetic switches.
New transgenic mice, which can be ablated both orexin neurons and MCH neurons, showed new brain state and revealed functional interaction that MCH neurons have protective role in narcolepsy symptoms.
Male-type aggressive and courtship behaviors of the fruit flies are differentially specified by two sex-determining genes, providing a substrate for the evolution to sculpt these two behaviors independently.
Generation of stable transgenic opsin lines together with in vivo calibration of their efficacy using behavioural and electrophysiological assays constitutes a novel optogenetic toolkit in zebrafish.
A combination of in vitro and in vivo experiments demonstrate a cell-autonomous role of the KIT ligand/KIT signaling pathway in protecting retinal photoreceptor cells from environmentally or genetically caused degeneration.
