Browse our latest Neuroscience articles

The developmental axon guidance receptor roundabout 2 maintains inhibitory synaptic connectivity in the adult brain; demonstrating continued essential function of this receptor in regulating synaptic function in the CNS.

Dysfunctions of myelin peroxisomes cause a lysosomal storage-like disorder associated with alterations in glial and axonal membranes, which is the likely cause of nerve impairment in peroxisomal disorders.

ATP imaging of spiking optic nerve axons in real time reveals correlation between ATP levels and electrical activity as well as contribution of lactate metabolism to axonal ATP homeostasis.

Actr10, a dynactin pointed end protein, is essential for mitochondrial interaction with the dynein-dynactin retrograde motor and subsequent transport.

In invertebrate and vertebrate models of Spinal Muscular Atrophy, diminished SMN protein causes Gemin3-dependent decreases in microRNA function, leading to upregulated M2 muscarinic receptor and deleterious consequences.

The contribution of biophysical ion channels to neuron function can be predicted by taking advantage of an ongoing dialogue between model and experiment.

Rapid increases in the brain’s level of alertness, or arousal, contribute to variability in decision making by reducing existing biases.

The remarkable lifelong stability of mechanotransducing stereocilia of the inner ear hair cells depends on the activity of the transduction ion channels located at the tips of these mechanosensory projections.

Map-like organisations of relational knowledge can be extracted from the hippocampal-entorhinal system in situations where relationships are non-spatial rather than spatial, discrete rather than continuous, and unavailable to conscious awareness.

Two theoretical studies reveal how networks of neurons may behave during reward-based learning.