Browse our latest Neuroscience articles

Page 502 of 603
    1. Developmental Biology
    2. Neuroscience

    A mutant with bilateral whisker to barrel inputs unveils somatosensory mapping rules in the cerebral cortex

    Nicolas Renier, Chloé Dominici ... Alain Chédotal
    The somatosensory cortex doesn't integrate mixed bilateral inputs, as partially uncrossing projections from the whiskers duplicates their representation by segregating lateralized inputs from each side of the head.
    1. Neuroscience

    Alzheimer’s Disease: Identifying faulty brain circuits

    Jesse E Hanson
    A protein called NPTX2 may be a useful marker of neural circuit defects in patients with Alzheimer's disease.
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    Insight
    1. Genetics and Genomics
    2. Neuroscience

    Variation in olfactory neuron repertoires is genetically controlled and environmentally modulated

    Ximena Ibarra-Soria, Thiago S Nakahara ... Darren W Logan
    The neuronal composition of a mouse’s nose is individually unique due to a combination of olfactory experience and genetic variation local to olfactory receptor genes.
    1. Cell Biology
    2. Neuroscience

    Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult

    Martin Larhammar, Sarah Huntwork-Rodriguez ... Trent A Watkins
    Two seemingly distinct cellular stress response pathways that contribute to neurodegeneration after axonal insults are now revealed to be under the control of a single master regulator of the neuronal injury response, the kinase DLK.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications

    Kaori Noridomi, Go Watanabe ... Lin Chen
    Autoantibodies from myasthenia gravis patients bind a common core region on the nicotinic acetylcholine receptor through a largely conserved mechanism.
    1. Neuroscience

    Steroid hormone induction of temporal gene expression in Drosophila brain neuroblasts generates neuronal and glial diversity

    Mubarak Hussain Syed, Brandon Mark, Chris Q Doe
    A steroid hormone acts directly on brain neural progenitors to coordinately alter gene expression and specify neuronal and glial cell types.
    1. Neuroscience

    EM connectomics reveals axonal target variation in a sequence-generating network

    Jörgen Kornfeld, Sam E Benezra ... Michael A Long
    Combining light microscopy and electron microscopy uncovered patterns of neural connectivity in a zebra finch forebrain region capable of generating song-related sequential activity, contributing to our understanding of the neural circuitry that underlies skilled motor performance.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition

    Li Hou, Pengcheng Yang ... Le Kang
    Two neuropeptides, NPF1a and NPF2, act via the nitric oxide signaling pathway in the locust brain to regulate the trait transition between solitary and swarming behavior.
    1. Cell Biology
    2. Neuroscience

    The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors

    Heather S Comstra, Jacob McArthy ... Victor Faundez
    The ATP7A interactome is the first comprehensive view of putative Menkes disease neurodegeneration mechanisms.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Identification of a pre-active conformation of a pentameric channel receptor

    Anaïs Menny, Solène N Lefebvre ... Pierre-Jean Corringer
    Allosteric reorganizations of a bacterial channel receptor are mapped along the protein structure, using the site-directed bimane quenching fluorescence technique, through parallel real-time conformational and electrophysiological recordings.