Browse our latest Neuroscience articles

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    1. Neuroscience

    Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

    Joan Font, Marc López-Cano ... Francisco Ciruela
    Localized drug photoactivation provides light-mediated analgesia in behaving mice.
    1. Neuroscience

    Emergence of transformation-tolerant representations of visual objects in rat lateral extrastriate cortex

    Sina Tafazoli, Houman Safaai ... Davide Zoccolan
    Neuronal recordings from rat visual cortex reveal an object-processing pathway, along which neuronal representations become increasingly capable of supporting recognition of visual objects in spite of variation in their appearance.
    1. Neuroscience

    A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity

    TD Barbara Nguyen-Vu, Grace Q Zhao ... Jennifer L Raymond
    Learning capacity depends on a dynamic interplay between the brain’s ability to change the strength of its synapses and the history of activity at those synapses.
    1. Neuroscience

    Analysis of the NK2 homeobox gene ceh-24 reveals sublateral motor neuron control of left-right turning during sleep

    Juliane Schwarz, Henrik Bringmann
    A genetic analysis has identified the cholinergic SIA sublateral motor neurons, which innervate all four body wall muscles separately, as crucial regulators of turning around during sleep in Caenorhabditis elegans.
    1. Neuroscience

    Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues

    Julieta E Lischinsky, Katie Sokolowski ... Joshua G Corbin
    Studying the development of the medial amygdala in the mouse reveals how the brain may potentially process sex differences in innate behaviors such as mating.
    1. Neuroscience

    Rules and mechanisms for efficient two-stage learning in neural circuits

    Tiberiu Teşileanu, Bence Ölveczky, Vijay Balasubramanian
    Teaching signals from "tutor" brain areas should be adapted to the plasticity mechanisms in "student" areas to achieve efficient learning in two-stage systems such as the vocal control circuit of the songbird.
    1. Neuroscience

    A causal relationship between face-patch activity and face-detection behavior

    Srivatsun Sadagopan, Wilbert Zarco, Winrich A Freiwald
    Disrupting the activity of the medial lateral face patch (ML) using fMRI-targeted microinjections of muscimol leads to anatomically and categorically specific impairments in a naturalistic face detection task.
    1. Neuroscience

    Fast-spiking GABA circuit dynamics in the auditory cortex predict recovery of sensory processing following peripheral nerve damage

    Jennifer Resnik, Daniel B Polley
    Dynamic regulation of feedforward inhibition from parvalbumin-expressing inhibitory neurons is linked to the gradual restoration of cortical sensory processing following auditory nerve damage.
    1. Neuroscience

    A cellular mechanism for inverse effectiveness in multisensory integration

    Torrey LS Truszkowski, Oscar A Carrillo ... Carlos D Aizenman
    Building on previous work (Felch et al., 2016), it is shown that inverse effectiveness, a central property of multisensory integration, in the optic tectum is mediated by the activation of NMDA-type glutamate receptors, resulting in a response greater than the sum of responses to each individual sensory modality.
    1. Neuroscience

    Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

    Yu Huang, Anli A Liu ... Lucas C Parra
    Direct in-vivo measurements in the human brain test validity of detailed computational models of trancranial electric stimulation and show that electric fields in the brain are weaker than currently assumed.