Minoru Koyama, Francesca Minale ... Joseph R Fetcho
Competition between neurons on the left and right sides of the brain drives the decision to turn left versus right in zebrafish, and potentially all vertebrates.
Uniting two principles that have been thought of being mutually exclusive in the past can explain how neurons become sensitive to the direction of motion.
A newly identified component in the architecture of the axon/myelin-unit – the septin/anillin scaffold – maintains the structure of myelin in the central nervous system, thereby preventing myelin outfoldings.
Maria N Zanetti, Oscar D Bello ... Shyam S Krishnakumar
A model for synchronous neurotransmitter release suggests that when not in the presence of calcium ions, Synaptotagmin proteins form ring-like structures between the vesicle and plasma membrane that prevent spontaneous fusion.
Andre Voelzmann, Pilar Okenve-Ramos ... Natalia Sanchez-Soriano
A novel regulatory cascade downstream of Tau and spectraplakins ensures that synaptic proteins are delivered to axonal terminals in the developing and ageing brain, providing potential explanations for precocious synapse loss in dementias.
Novel brainstem organotypic cultures that generate rhythmic respiratory motor activity reveal the neural networks that control breathing and a new pathway in the hypercapnic response.