Browse our latest Neuroscience articles

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    1. Neuroscience

    The DEG/ENaC cation channel protein UNC-8 drives activity-dependent synapse removal in remodeling GABAergic neurons

    Tyne W Miller-Fleming, Sarah C Petersen ... David M Miller III
    The protein UNC-8 is a neuronal activity sensor that triggers the elimination of synapses during development of the nervous system.
    1. Neuroscience

    Hippocampal pattern completion is linked to gamma power increases and alpha power decreases during recollection

    Bernhard P Staresina, Sebastian Michelmann ... Juergen Fell
    Direct recordings from the human hippocampus reveal the neural mechanisms that orchestrate recollection of past experiences.
    1. Neuroscience

    A circuit motif in the zebrafish hindbrain for a two alternative behavioral choice to turn left or right

    Minoru Koyama, Francesca Minale ... Joseph R Fetcho
    Competition between neurons on the left and right sides of the brain drives the decision to turn left versus right in zebrafish, and potentially all vertebrates.
    1. Neuroscience

    Complementary mechanisms create direction selectivity in the fly

    Juergen Haag, Alexander Arenz ... Alexander Borst
    Uniting two principles that have been thought of being mutually exclusive in the past can explain how neurons become sensitive to the direction of motion.
    1. Neuroscience

    A shared numerical representation for action and perception

    Giovanni Anobile, Roberto Arrighi ... David Charles Burr
    Adapting to rapid or slow finger tapping selectively biases the apparent numerosity of sequences or arrays of visual stimuli.
    1. Neuroscience

    Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction

    Julia Patzig, Michelle S Erwig ... Hauke B Werner
    A newly identified component in the architecture of the axon/myelin-unit – the septin/anillin scaffold – maintains the structure of myelin in the central nervous system, thereby preventing myelin outfoldings.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Ring-like oligomers of Synaptotagmins and related C2 domain proteins

    Maria N Zanetti, Oscar D Bello ... Shyam S Krishnakumar
    A model for synchronous neurotransmitter release suggests that when not in the presence of calcium ions, Synaptotagmin proteins form ring-like structures between the vesicle and plasma membrane that prevent spontaneous fusion.
    1. Developmental Biology
    2. Neuroscience

    Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking

    Andre Voelzmann, Pilar Okenve-Ramos ... Natalia Sanchez-Soriano
    A novel regulatory cascade downstream of Tau and spectraplakins ensures that synaptic proteins are delivered to axonal terminals in the developing and ageing brain, providing potential explanations for precocious synapse loss in dementias.
    1. Cell Biology
    2. Neuroscience

    Proneurotrophin-3 promotes cell cycle withdrawal of developing cerebellar granule cell progenitors via the p75 neurotrophin receptor

    Juan Pablo Zanin, Elizabeth Abercrombie, Wilma J Friedman
    The p75 neurotrophin receptor regulates when granule neuron progenitors exit the cell cycle in the developing cerebellum.
    1. Computational and Systems Biology
    2. Neuroscience

    CO2-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture

    David Forsberg, Zachi Horn ... Eric Herlenius
    Novel brainstem organotypic cultures that generate rhythmic respiratory motor activity reveal the neural networks that control breathing and a new pathway in the hypercapnic response.