Browse our latest Neuroscience articles

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    1. Neuroscience

    Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain

    Jake F Watson, Hinze Ho, Ingo H Greger
    The positioning of AMPA-type glutamate receptors at synapses – a requirement for effective neurotransmission and synaptic plasticity – is orchestrated by their extracellular, N-terminal domain.
    1. Neuroscience

    Dopamine signaling tunes spatial pattern selectivity in C. elegans

    Bicheng Han, Yongming Dong ... Jihong Bai
    Natural variations in touch-dependent dopamine signaling tune the perception of spatial patterns in C. elegans.
    1. Neuroscience

    Neuromodulation: Transcranial electric stimulation seen from within the brain

    Angel V Peterchev
    Computer models can make transcranial electric stimulation a better tool for research and therapy.
    Version of Record
    Insight
    1. Neuroscience

    Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects

    Romana Tomasoni, Raffaella Morini ... Michela Matteoli
    Excessive inflammation of the brain in early life predisposes individuals to neurodevelopmental disorders by preventing synapses from developing correctly.
    1. Neuroscience

    Detecting changes in dynamic and complex acoustic environments

    Yves Boubenec, Jennifer Lawlor ... Bernhard Englitz
    Psychophysics experiments and EEG recordings reveal that people's performance in detecting unexpected changes in complex auditory scenes can be modeled as a process of sensory evidence accumulation.
    1. Immunology and Inflammation
    2. Neuroscience

    Peptidoglycan sensing by octopaminergic neurons modulates Drosophila oviposition

    C Leopold Kurz, Bernard Charroux ... Julien Royet
    Female fruit flies sense bacteria-derived peptidoglycan via the octopaminergic neurons to adapt their egg laying behavior to their infection status.
    1. Neuroscience

    NPTX2 and cognitive dysfunction in Alzheimer’s Disease

    Mei-Fang Xiao, Desheng Xu ... Paul F Worley
    Dysfunction of pyramidal neuron-PV interneuron circuits contributes to cognitive failure in Alzheimer's disease.
    1. Cell Biology
    2. Neuroscience

    Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice

    Ruchira Sharma, Yoshiro Ishimaru ... Hiroaki Matsunami
    G protein-coupled odorant receptors regulate their own gene transcription based on their cell surface trafficking, which is facilitated by receptor transporting protein (RTP) family members.
    1. Neuroscience

    Neural markers of predictive coding under perceptual uncertainty revealed with Hierarchical Frequency Tagging

    Noam Gordon, Roger Koenig-Robert ... Jakob Hohwy
    The novel neural marker for the integration of top-down predictions and bottom-up signals in perception elucidates uncertainty in perceptual inference and provides evidence for the predictive coding account of perception.
    1. Neuroscience

    Activity patterns of serotonin neurons underlying cognitive flexibility

    Sara Matias, Eran Lottem ... Zachary F Mainen
    Recordings from serotonin-producing neurons in the brain reveal that these neurons are highly activated by sudden changes in previously familiar environments, potentially explaining why serotonin is important for learning to adapt to such changes.