A biologically plausible learning rule allows recurrent neural networks to learn nontrivial tasks, using only sparse, delayed rewards, and the neural dynamics of trained networks exhibit complex dynamics observed in animal frontal cortices.
Transcription factors that specify the identity of individual neuron types via activating terminal differentiation gene batteries also restrict cellular plasticity via altering the chromatin landscape.
Somatostatin-expressing interneurons of the rodent dentate gyrus fall into at least two functionally distinct interneuron types with different synaptic integrations into the local dentate gyrus and the more distant medial septum neuronal network.
Robert G Rasmussen, Andrew Schwartz, Steven M Chase
Motor neurons adjust their sensitivity to direction of movement in a manner analogous to how neurons in the visual system adjust their sensitivity to light.
A computational model explains how the brain chooses between creating a new memory versus updating an old one when faced with an event that defies expectations.
Building on previous work (Metzen et al., 2016), a combination of neurophysiological and behavioral approaches reveals that changes in the background strongly impacts invariant coding and perception of behaviourally relevant signals.
Abigail M Polter, Kelsey Barcomb ... Julie A Kauer
Rats exposed to a single stressful event experience days-long constitutive activation of the kappa opioid receptor at inhibitory synapses in part of the brain’s reward system, which increases their drug-seeking behavior.
Although sugar-sensing taste neurons typically promote feeding, a taste neuron in the Drosophila pharynx limits feeding via the IR60b receptor; thus, revealing a new element in the circuit logic of feeding control.