Katie Morris, Edita Bulovaite ... Mathew H Horrocks
PSD95 supercomplexes maintain long-term stability through gradual subunit replacement, with the slowest turnover in cortical synapses associated with memory storage.
John P Grogan, Matthias Raemaekers ... Sanjay G Manohar
Muscarinic antagonism is causally involved in motivation and incentivisation in healthy human participants, partially mediated via preparatory neural signatures, with implications for cholinergic treatment of Parkinson's disease.
Samyogita Hardikar, Bronte Mckeown ... Jonathan Smallwood
Interactions between attention systems and the default mode network are linked to individual differences in trait and state-level experience and cognition.
The results of central nervous regulation in mice provide a new neural circuit and receptor regulatory mechanisms for the recovery of consciousness after midazolam administration.
Although activity in mouse V1 increases substantially during volitional running, such modulations in the foveal/central representation of primate V1 appear much smaller and suppressive.
Mighten C Yip, Mercedes M Gonzalez ... Craig R Forest
Patch-walking is a novel automated patch clamp approach for finding synaptic connections in brain tissue, yielding 80–92% more probed connections than traditional approaches.
Human intracranial electroencephalography recordings across 177 participants and four diverse episodic memory experiments demonstrate how the anterior insula node of the salience network orchestrates dynamics of large-scale brain networks.
Changes in cortical neural ensembles and heightened coupling between the hippocampus and cortex enable the eventual behavioral integration of memories with overlapping sequential information.