A temporally stable and cell-type-specific genetic driver library provides the means to access and manipulate neuronal lineages in the fly nervous system during development and adulthood.
A dynamic DNA methylation 'barcode' on the X chromosome can distinguish thousands of individual adult male neurons and may record aspects of their development.
Yevheniia Ishchenko, Amanda T Jeng ... Anthony J Koleske
Heterozygosity for Trio variants leads to overlapping but distinct impacts on behavior, neuronal structure, and synaptic transmission, including newly characterized defects in presynaptic function.
During reaching in mice, forelimb premotor cortex has a stronger influence on primary motor cortex than vice versa, but several functional connectivity measures fail to reflect this asymmetry.
Beta synchrony between motor cortex and the subthalamic nucleus is intensified when instructional cues within a continuous motor sequence become less predictable, calling for more cautious behavior.