Browse our latest Physics of Living Systems articles

Quantitative measurement of epigenetic memory and inheritance dynamics.

Upon DNA damage, Rad52 forms a membraneless sub-compartment where Rad52 molecules are highly dynamic and share properties with liquid-liquid phase-separated molecules, reflecting the existence of a liquid droplet around damaged DNA.

Dual resin casting of multiple lumenized systems followed by microCT allows visualization, digitalization, and quantification of architectural parameters defining the vascular and biliary systems in liver revealing new phenotypes.

Combining global and local force measurements of reconstituted muscle tissue using a new chamber system that is compatible with high-resolution microscopy shows mechanical homeostasis already within a week.

Charge complementarity between RNA and proteins may be a universal principle for phase separation in biology without requiring disorder or specific multivalent interactions.

The rapid development of immune memory in infancy shapes the composition of T cell defenses throughout the human lifespan.

Spontaneous elongation of epithelial colonies is related to the orientation of the mean nematic cell elongation field, as shown and tested with experiments and theory.

A new imaging modality is described that can simultaneously record from several dishes without using robotics, which enables researchers to perform high-throughput, continuous measurements on biological samples.

Asymmetric forward and backward swimming speeds reveal that the rotational bias, and not reversal frequencies, is an appropriate measure of chemotaxis signaling in Helicobacter pylori..

Theoretical study shows how enzymes can achieve substrate proofreading by taking advantage of existing molecular gradients in the cell while not being endowed with structural features typically required for proofreading.