Browse our latest Physics of Living Systems articles

Page 8 of 57
    1. Physics of Living Systems

    Differential spatial regulation and activation of integrin nanoclusters inside focal adhesions

    Sarah Keary, Nicolas Mateos ... Maria F Garcia-Parajo
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Physics of Living Systems

    Cell cycle and age-related modulations of mouse chromosome stiffness

    Ning Liu, Wenan Qiang ... Huanyu Qiao
    Mammalian condensed chromosomes exhibit diverse structural properties, as reflected in their varying stiffness across different cell stages and with aging.
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    A mathematical model clarifies the ABC Score formula used in enhancer-gene prediction

    Joseph Nasser, Kee-Myoung Nam, Jeremy Gunawardena
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Physics of Living Systems

    Endurance Exercise Ameliorates Aging-Related Bradyarrhythmia in Drosophila Resulting from miR-283 Knockdown in LNvs

    Qiufang Li, Xu Ping ... Lan Zheng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cancer Biology
    2. Physics of Living Systems

    Mechanistic insight for T-cell exclusion by cancer-associated fibroblasts in human lung cancer

    Joseph Ackermann, Chiara Bernard ... Martine D Ben Amar
    The crosstalk between cancerous lesions and the immune system in the lungs demonstrates the complex role of fibroblasts.
    1. Neuroscience
    2. Physics of Living Systems

    Annihilation of action potentials induces electrical coupling between neurons

    Moritz Schloetter, Georg U Maret, Christoph J Kleineidam
    Action potentials of neurons expel a charge when they reach the axon terminal, and classical electrodynamics predict the resulting electric fields and its influence to other neurons by ephaptic coupling.
    1. Physics of Living Systems

    Modularity of the segmentation clock and morphogenesis

    James E Hammond, Ruth E Baker, Berta Verd
    Computational modelling suggests that the segmentation clock and the morphogenesis of the pre-somitic mesoderm exhibit developmental modularity, enabling the independent evolution of these processes and possibly contributing to the high evolvability of vertebrate segment number.
    1. Physics of Living Systems

    Emergence of ion-channel-mediated electrical oscillations in Escherichia coli biofilms

    Emmanuel Akabuogu, Victor Carneiro da Cunha Martorelli ... Thomas A Waigh
    Electrical signaling is demonstrated in Escherichia coli biofilms.
    1. Cell Biology
    2. Physics of Living Systems

    A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits

    Krishna Rijal, Pankaj Mehta
    A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical networks with desired input–output relationships.
    1. Physics of Living Systems

    Emergence of alternative stable states in microbial communities undergoing horizontal gene transfer

    Juken Hong, Wenzhi Xue, Teng Wang
    Mathematical models of horizontal gene transfer reveal the determinants underlying multistability of microbial communities, offering key insights for the predictive control and engineering of complex microbiota.