Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cell-free DNA as a potential biomarker of differentiation and toxicity in cardiac organoids

    Brian Silver, Kevin Gerrish, Erik Tokar
    Cardiac organoids have potential as a tool used for identifying cell-free DNA as biomarkers for toxicity and severity of exposure outcomes.
    1. Stem Cells and Regenerative Medicine

    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

    Yaeko Nakajima-Takagi, Motohiko Oshima ... Atsushi Iwama
    Polycomb repressive complex 1.1 restricts precocious myeloid differentiation of hematopoietic stem/progenitor cells and expansion of myeloid progenitors, thereby serving as a gatekeeper of emergency myelopoiesis and myeloid transformation.
    1. Stem Cells and Regenerative Medicine

    Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice'

    Anne Sustar, John C Tuthill
    We are writing to comment on the article by Abrams et al., 2021 about appendage regeneration in jellyfish, fruit flies, and mice.
    1. Evolutionary Biology
    2. Stem Cells and Regenerative Medicine

    Response to comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice'

    Yutian Li, Anish A Sarma ... Lea Goentoro
    We are writing to respond to the comment by Sustar and Tuthill, 2023 on our article about appendage regeneration in jellyfish, fruit flies, and mice (Abrams et al., 2021).
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Brain Development: The dangers of rubella virus

    Ekaterina Epifanova, Laurent Nguyen
    The rubella virus can interfere with fetal brain development by infecting immune cells called microglia during pregnancy.
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity

    Claudia Dominici, Oscar D Villarreal ... Stéphane Richard
    Inhibition of type I PRMTs increases the proliferation capabilities of MuSCs with altered cellular metabolism, while maintaining their stem-like properties such as self-renewal and engraftment potential.
    1. Stem Cells and Regenerative Medicine

    Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors

    Claudia Dell'Amico, Marilyn M Angulo Salavarria ... Marco Onorati
    Microcephaly-associated mutations disrupt microtubule-dependent WDR62 translocation from the Golgi complex to the mitotic spindle poles, impair mitotic progression, and alter neurogenic trajectories in patient induced Pluripotent Stem Cell-derived 2D and 3D models of human neurodevelopment.
    1. Stem Cells and Regenerative Medicine

    Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle

    Nurul Jannah Mohamed Nasir, Hans Heemskerk ... Lisa Tucker-Kellogg
    Myoglobin iron contributes to the formation and poor healing of muscle pressure injuries, that is, bedsores, and iron-chelation therapy can be administered after prolonged pressure to increase survival of the damaged tissue.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration

    Terren K Niethamer, Lillian I Levin ... Edward E Morrisey
    After acute lung injury, the transcription factor Atf3 is essential for regeneration of the capillary endothelium, which is critical for restoring the structure of the lung alveolus.
    1. Stem Cells and Regenerative Medicine

    Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis

    Rachel Warren, Handeng Lyu ... Stijn P De Langhe
    Alveolar type 2 stem cells are actively maintained by Hippo signaling and Taz promotes alveolar epithelial regeneration and the resolution of bleomycin induced pulmonary fibrosis upon inactivation of the Hippo pathway in Alveolar type 2 stem cells.