Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Stem Cells and Regenerative Medicine

    Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells

    Sicong He, Jiahao Chen ... Jin Xu
    Adult zebrafish Langerhans cells are derived from hematopoietic stem/progenitor cells but not Erythro-myeloid progenitors.
    1. Chromosomes and Gene Expression
    2. Stem Cells and Regenerative Medicine

    SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program

    Madara Ratnadiwakara, Stuart K Archer ... Minna-Liisa Anko
    RNA-binding protein SRSF3 mediates critical changes in RNA processing of pluripotency genes, which reveals functional consequences of regulated RNA processing during stem cell self-renewal and early development.
    1. Stem Cells and Regenerative Medicine

    Live cell-lineage tracing and machine learning reveal patterns of organ regeneration

    Oriol Viader-Llargués, Valerio Lupperger ... Hernán López-Schier
    A combination of live cell tracking, cell-lineage tracing and machine learning shows that injured sensory organs repair accurately regardless of the extent of damage.
    1. Cancer Biology
    2. Stem Cells and Regenerative Medicine

    Stem Cell Tumors: Cherub versus brat

    Jennifer A Malin, Claude Desplan
    A long non-coding RNA molecule called cherub is a driver of tumor development.
    Version of Record
    Insight
    1. Cancer Biology
    2. Stem Cells and Regenerative Medicine

    The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells

    Lisa Landskron, Victoria Steinmann ... Jürgen A Knoblich
    Genetic analyses uncovered that the asymmetrically long non-coding RNA cherub is required for brain tumor growth.
    1. Stem Cells and Regenerative Medicine

    Positional information specifies the site of organ regeneration and not tissue maintenance in planarians

    Eric M Hill, Christian P Petersen
    Homeostatic tissue maintenance can occur at locations distinct from the target sites of organ regeneration planarians.
    1. Stem Cells and Regenerative Medicine

    Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis

    Isabelle Bergiers, Tallulah Andrews ... Christophe Lancrin
    Single-cell transcriptomics analysis identifies the dynamic activity of transcription factors at the onset of hematopoeitic stem and progenitor cells formation during embryonic development.
    1. Stem Cells and Regenerative Medicine

    ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response

    Richard H Chapple, Tianyuan Hu ... Daisuke Nakada
    Estrogen is a systemic factor that promotes hematopoietic regeneration by activating the unfolded protein responses.
    1. Stem Cells and Regenerative Medicine

    CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs

    Melanie I Worley, Larissa A Alexander, Iswar K Hariharan
    The CtBP protein stabilizes cell fates in regenerating tissue.
    1. Stem Cells and Regenerative Medicine

    Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina

    Katharina Lust, Joachim Wittbrodt
    Müller glia cells in the medaka (Oryzias latipes) retina act as lineage restricted progenitors which only regenerate photoreceptors but can be activated to perform as potent stem cells using Sox2.