Browse our latest Structural Biology and Molecular Biophysics articles

The principal potassium ion channel in human sperm, Slo3, is primarily activated by calcium ions and controls the membrane potential of human sperm by intracellular calcium ion levels rather than intracellular pH.

Bacterial cytoplasmic chemoreceptors assemble into a sandwich of two hexagonally packed arrays.

The three-dimensional structures of 50 sensory cilia present in the head of the adult C. elegans hermaphrodite have been reconstructed to provide a foundation for investigations into the mechanisms by which the diversity of cilia structures is generated and how this structural diversity is related to specific sensory neuron functions.

Phosphorylation of the Wnt receptor LRP6 directly inhibits glycogen synthase kinase-3 by acting as a pseudosubstrate that stabilizes an active conformation of the enzyme, identical to autoinhibition by phosphorylation of its N terminus.

A combination of imaging experiments and computer simulations on a model lipid membrane integrate the 'picket fence' and 'raft' models, and suggest that the interplay between actin binding, lipid phase separation and curvature compartmentalize the membrane.

Peptide and nitrate transporters have been converted into fluorescent reporters of transport activity and have been used to measure various transport properties including the dual affinity of the nitrate transceptor

The X-ray structure of the SAS-6 cartwheel hub from Leishmania major demonstrates that SAS-6 can be sufficient to determine centriolar cartwheel symmetry.