Browse our latest Structural Biology and Molecular Biophysics articles

The flavoprotein NrdI in class Ib ribonucleotide reductase controls superoxide generation and metal site oxidation by tuning the redox properties of its flavin cofactor via steric strain induced by the formation of the R2b–NrdI protein complex.

Arc-shaped PFO oligomers consisting of at least four subunits can insert into the membrane in a kinetically controlled process opening a transmembrane pore, whereby post-insertion growth may ultimately lead to formation of a complete ring.

Structural, functional, and genetic analyses reveal how kinesin-4 motor KLP-12 precisely modulates the curvature of the microtubule plus-end to inhibit the microtubule dynamics for achieving the proper length control of axons.

A viral heliorhodopsin from Emiliania huxleyi virus 202 (V2HeR3) is a light-activated proton transporter, which has the potential to depolarize the host cells by light, possibly to overcome the host defense mechanisms or to prevent superinfection.

Comparing the relative similarity of cellular molecules to alternate templates allows classification of related complexes in the cell using fewer particles than needed for 3D classification and is more practicable for low abundance complexes.

Comparisons of enzyme efficiency and electron transfer show that, to oxidize water using lower energy light, the two types of far-red photosystem II have adopted opposite trade-offs between efficiency of light use and resilience to light damage.

Two species of photosynthetic cyanobacteria can thrive in far-red light but they either become less resilient to photodamage or less energy efficient.

The yeast U1 snRNP recognizes multiple features of target RNAs to reversibly identify splicing-competent 5' splice sites.

Structure of M. tuberculosis Rv1625c/Cya provides clues to the potential functional role of the transmembrane domain in the membrane adenylyl cyclases.

A novel dual-site binding between the yeast t-SNARE Sso2 and Sec3 (a component of the exocyst tethering complex) facilitates the fusion of secretory vesicles with the plasma membrane.