Machine learning models effectively predict the risk of post-stroke epilepsy using extensive clinical data, offering new insights for improving patient management in clinical neurology.
Alejandro J Brenes, Eva Griesser ... Angus I Lamond
Human induced pluripotent stem cells and embryonic stem cells express a similar set of proteins, but the levels of cytoplasmic and mitochondrial proteins vary, with concomitant effects on phenotypes including transport and mitochondrial function.
A novel pair of isobaric crosslinking reagents is described, which allow relative quantification of crosslinker-modified peptides during mass spectrometry analysis for comparative structural studies of proteins and protein complexes.
Gaetan De Waele, Gerben Menschaert, Willem Waegeman
It is possible to accurately recommend antimicrobial drugs from mass spectra using neural networks and large datasets, paving the way for more efficient clinical diagnostics.
The binding site and potential mechanism of human SCARF1 for lipoprotein recognition are identified by combining the crystal structural determination of the N-terminal fragments and biochemical and cellular assays.