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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Biochemical and structural insights into the auto-inhibited state of Mical1 and its activation by Rab8

    Amrita Rai, Petra Janning ... Roger S Goody
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Integration of overlapping sequences emerges with consolidation through medial prefrontal cortex neural ensembles and hippocampal–cortical connectivity

    Alexa Tompary, Lila Davachi
    Changes in cortical neural ensembles and heightened coupling between the hippocampus and cortex enable the eventual behavioral integration of memories with overlapping sequential information.
    1. Neuroscience

    Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury

    Qing Zhao, Yanjing Zhu ... Ning Xie
    Selectively eliminating resident astrocytes in lumbar enlargement attenuated neuropathic pain associated with type I interferons (IFNs) signal activation in microglia.
    1. Neuroscience

    Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex

    Ruggiero Francavilla, Bidisha Chattopadhyaya ... Graziella Di Cristo
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Increased listening effort and cochlear neural degeneration underlie behavioral deficits in speech perception in noise in normal hearing middle-aged adults

    Maggie E Zink, Leslie Zhen ... Aravindakshan Parthasarathy
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Synaptic connectome of a neurosecretory network in the Drosophila brain

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Ecology
    2. Physics of Living Systems

    Colony demographics shape nest construction in ants

    Harikrishnan Rajendran, Roi Weinberger ... Ofer Feinerman
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Oxytocin salvages context-specific hyperaltruistic preference through moral framing

    Hong Zhang, Yinmei Ni, Jian Li
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology

    Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785

    Shan Zhang, Robyn Stix ... José D Faraldo-Gómez
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Evolutionary Biology

    Reversion to sensitivity explains limited transmission of resistance in a hospital pathogen

    Kevin C Tracy, Jordan McKaig ... Robert J Woods
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
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