Browse our latest research

Page 175 of 1,897
    1. Neuroscience

    How Occam’s razor guides human decision-making

    Eugenio Piasini, Shuze Liu ... Joshua I Gold
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Persistent contacts between Climp63 and microtubules cause mitotic defects and nuclear fragmentation

    Jelmi uit de Bos, Ulrike Kutay
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    EEG decodability of facial expressions and their stereoscopic depth cues in immersive virtual reality

    Felix Klotzsche, Ammara Nasim ... Michael Gaebler
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Human neurocomputational mechanisms of guilt-driven and shame-driven altruistic behavior

    Ruida Zhu, Huanqing Wang ... Chao Liu
    Harm and responsibility differentially shape guilt and shame, which in turn drive compensatory behavior to varying extents.
    1. Stem Cells and Regenerative Medicine

    Glycogen engineering improves the starvation resistance of mesenchymal stem cells and their therapeutic efficacy in pulmonary fibrosis

    Yongyue Xu, Mamatali Rahman ... Qiong Wu
    Glycogen engineering strategies of mammalian cells were developed, which improved the survival of mesenchymal stem cells post-implantation and their therapeutic efficacy in pulmonary fibrosis model.
    1. Biochemistry and Chemical Biology

    Deep learning reveals endogenous sterols as allosteric modulators of the GPCR–Gα interface

    Sanjay Kumar Mohanty, Aayushi Mittal ... Gaurav Ahuja
    An AI-driven computational toolkit, Gcoupler, integrates ligand design, statistical modeling, and graph neural networks to predict endogenous metabolites that allosterically modulate the GPCR–Gα interface and regulate downstream signaling.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A modular platform to display multiple hemagglutinin subtypes on a single immunogen

    Dana Thornlow Lamson, Faez Amokrane Nait Mohamed ... Aaron G Schmidt
    BOAS is a platform for building multivalent viral protein immunogens without a scaffold, such as a nanoparticle, to elicit broad influenza vaccine responses.
    1. Physics of Living Systems

    Theory of active self-organization of dense nematic structures in the actin cytoskeleton

    Waleed Mirza, Marco De Corato ... Marino Arroyo
    Theoretical and computational modeling reveals a mechanism of active patterning of uniform isotropic actin gels into dense nematic bundles, providing a physical basis for the adaptability of the actin cytoskeleton.
    1. Neuroscience

    Rapid rebalancing of co-tuned ensemble activity in the auditory cortex

    HiJee Kang, Travis A Babola, Patrick O Kanold
    Holographic neuronal stimulation shows that auditory cortex neurons with shared functional properties rapidly adjust their responses during sensory processing, revealing a circuit-level mechanism that regulates overall network activity balance.
    1. Microbiology and Infectious Disease

    PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

    Binayak Sarkar, Jyotsna Singh ... Rajesh S Gokhale
    In vitro, ex vivo, and in vivo studies reveal that hepatocytes are significantly infected by Mycobacterium tuberculosis which rewires the host cell metabolism to upregulate the lipid biosynthetic pathways.