Mouse embryo cells undergo apical-basal polarization asynchronously at the 8-cell stage, and the timing of polarization influences subsequent lineage allocation.
An evolutionary perspective on immune priming across plants and invertebrates highlights the roles of microbiomes and epigenetic regulation in shaping innate immune memory with promising applications in agriculture and aquaculture.
Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing
Children show less robust memory retention overnight and after 2 weeks, with memories transforming more rapidly from detailed to gist-like neural representations, revealing less stable consolidation mechanisms than in adults.
Quantitative Drosophila pupal wing experiments support planar polarity depending on cell-scale signalling that does not involve depletion of a limited pool of core proteins or polarised transport on microtubules.
A holistic narrative describes how extracellular matrices regulate various aspects of the entire leukocyte journey from blood to inflamed tissue, and the subsequent functional impacts on leukocyte and tissue fates.
Alma Carolina Sanchez Rocha, Mikhail Makarov ... Klára Hlouchová
Amino acids that were abundant since the prebiotic era are enriched in protein binding sites of the most ancient coenzymes, supporting the plausibility of an early coenzyme–peptide world.
