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Page 291 of 1,744
    1. Neuroscience

    Finding structure during incremental speech comprehension

    Bingjiang Lyu, William D Marslen-Wilson ... Lorraine K Tyler
    Structural representations of sentences generated by deep language models correlate with human listeners' behaviours and neural activity, providing a quantifiable framework to uncover the neural dynamics underpinning incremental speech comprehension.
    1. Neuroscience

    Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers

    Matthias Heindorf, Georg B Keller
    Cell type-specific effects of antipsychotic drugs in cortex could provide a basis for a functional screen of antipsychotic efficacy.
    1. Chromosomes and Gene Expression

    Post-transcriptional splicing can occur in a slow-moving zone around the gene

    Allison Coté, Aoife O'Farrell ... Arjun Raj
    The existence of a slow-moving zone around the transcription site may unify conflicting models of co-transcriptional versus post-transcriptional mRNA splicing.
    1. Neuroscience

    Maturation of cortical input to dorsal raphe nucleus increases behavioral persistence in mice

    Nicolas Gutierrez-Castellanos, Dario Sarra ... Zachary F Mainen
    Anatomical tracing, in combination with a genetic ablation approach, identifies a critical maturation period for neocortex to dorsal raphe afferents pivotal for the development of behavioral persistence over adolescence in mice.
    1. Physics of Living Systems

    Theory of active self-organization of dense nematic structures in the actin cytoskeleton

    Waleed Mirza, Marco De Corato ... Marino Arroyo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Evolutionary Biology

    ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

    Eman Hijaze, Tsvia Gildor ... Smadar Ben-Tabou de-Leon
    ROCK and the actomyosin network are essential for multiple aspects of sea urchin skeletogenesis, suggesting an independent deployment of these factors in biomineralization across Eukaryotes.
    1. Cancer Biology

    STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer

    Stephen D'Amico, Varvara Kirillov ... Nancy C Reich
    Results show that STAT3 and KRAS jointly regulate oncogenic dependency of mutant KRAS cancer cells.
    1. Medicine

    Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia

    Ling Zhou, Chengyang Ni ... Jianming Wu
    Vilazodone could bind to the 5-Hydroxtrayptamine receptor 1A receptor and further regulate the SRC/MAPK signaling pathway to facilitate megakaryocyte differentiation and platelet production.
    1. Chromosomes and Gene Expression

    Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

    Fujun Zhou, Julie M Bocetti ... Jon R Lorsch
    A new in vitro approach allows measurement of the efficiency of the early steps of translation initiation on every messenger RNA in yeast simultaneously.
    1. Developmental Biology
    2. Genetics and Genomics

    Disruption in CYLC1 leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and mice

    Hui-Juan Jin, Yong Fan ... Su-Ren Chen
    Cylicin-1, a perinuclear theca protein, is critical for acrosome attachment and sperm head morphology.