Browse our latest research

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    1. Neuroscience

    The influence of sample size and covariate distributions on neuroanatomical normative modeling

    Camille Elleaume, Bruno Hebling Vieira ... Nicolas Langer
    Systematic analyses show that normative model performance strongly depends on sample size and covariate distributions, larger samples yield more stable fits, while misaligned covariates introduce systematic distortions in predictions.
    1. Structural Biology and Molecular Biophysics

    Structure of the human CTF18−RFC clamp loader bound to PCNA

    Giuseppina R Briola, Mohammad Tehseen ... Alfredo De Biasio
    Human CTF18–RFC employs a unique structural stabilization mechanism to optimize PCNA loading and stimulate DNA synthesis by the leading-strand polymerase.
    1. Neuroscience

    Strong mnemonic prediction errors increase cognitive control, attention, and arousal

    Alice M Xue, Jenna Jokhani ... Anthony D Wagner
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome

    Beth A Shen, Kyle L Asfahl ... Joseph D Mougous
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Multi-barrier unfolding of the double-knotted protein, TrmD–Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

    Fernando Bruno da Silva, Szymon Niewieczerzal ... Joanna I Sulkowska
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Death receptor 6 does not regulate axon degeneration and Schwann cell injury responses during Wallerian degeneration

    Bogdan Beirowski, Haoran Huang, Elisabetta Babetto
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation

    Ellen Späth, Svenja C Schüler ... Alessandro Ori
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    Cytoplasmatic polyadenylation of mRNA by TENT5A is critical for enamel mineralization

    Goretti Aranaz-Novaliches, Olga Gewartowska ... Jan Prochazka
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease

    A macroevolution-inspired approach to reveal novel antibiotic resistance mechanisms

    Fernanda T Subtil, Teresa FG Machado ... Luiz Pedro S de Carvalho
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing