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    1. Neuroscience

    Neural activity profiles reveal overlapping, intermingled subpopulations spanning area borders in mouse sensorimotor cortex

    Sohrab Salimian, Harrison Grier, Matthew Tyler Kaufman
    Single neurons in mouse sensorimotor cortex are organized by their activity features into distinct subpopulations with area-spanning footprints whose boundaries align closely with anatomical and somatotopic borders.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Non-canonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy

    Hao Chen, Haocheng Wang ... Jiou Wang
    Minimally disruptive genetic code expansion enables faithful, site-specific labeling of G3BP1 and TDP-43, revealing native stress granule dynamics and ALS-linked protein behavior in live cells.
    1. Medicine

    Navigating the path: Advice to physician-scientists on choosing a clinical specialty

    Talia Swartz, Jose E Cavazos ... Christopher S Williams
    This article provides critical insights in guiding aspiring physician-scientist medical students on how to choose a clinical specialty.
    1. Neuroscience

    A battery of image classification challenges reveals shared and distinct object categorization behavior across monkeys, humans, and deep networks

    Han Zhang, Zhihao Zheng ... Gouki Okazawa
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology

    Nuclear export modulates TDP-43 phase transition and cytoplasmic aggregation

    Natalie Chin, Qi Zhang ... Yihong Ye
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Developmental Biology

    Genome-wide discovery of cis-regulatory elements in a large genome

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Midbrain somatostatin-expressing cells control pain-suppression during defensive states

    Nanci Winke, Frank Aby ... Cyril Herry
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Exceptional
    1. Immunology and Inflammation

    Application of Engineered NK-92 Cell Extracellular Vesicles in the Treatment of Systemic Lupus Erythematosus

    Yu Sun, Zeyu Tang ... Xiaowei Dou
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair

    James S White, Junmin Hua ... Andrea Page-McCaw
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Membrane contact site resident PTP1B limits superoxide production by suppressing a Syk-Shc1-Phagocyte Oxidase relay

    Minhyoung Lee, Haggag S Zein ... Gregory D Fairn
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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