Browse our latest research

Page 29 of 1,858
    1. Medicine

    Platelets promote acute liver injury via extracellular vesicles-mediated Aldolase A

    Ruoxue Yang, Jinghua Liu ... Zhao Shan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    SETD6-mediated methylation of PPARγ establishes a transcriptional feedback circuit promoting lipid accumulation in liver-derived cells

    Noa Nashnaz, Dana Goldberg ... Dan Levy
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Effort produces after-effects costly for others but valued for self

    Ya Zheng, Rumeng Tang
    Neural reward signals following effort are amplified for self-benefiting outcomes but attenuated for other-benefiting outcomes, contingent upon reward magnitude and individual effort sensitivity.
    1. Chromosomes and Gene Expression

    Identification of the regulatory elements and protein substrates of lysine acetoacetylation

    Qianyun Fu, Terry Nguyen ... Y George Zheng
    A newly developed chemo-immunological strategy enabled detection of acetoacetate-mediated lysine acetoacetylation, identified the associated regulatory enzymes, and revealed its distinct biological functions and physiological significance.
    1. Neuroscience

    A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory

    Elena Badillo Goicoechea, Phillip F Agres ... Joel L Voss
    Meta-analysis indicates that network-targeted non-invasive brain stimulation consistently enhances memory function supported by the hippocampal network, thus providing robust evidence that specific memory abilities rely on specific modifiable brain networks.
    1. Neuroscience

    Subregional activity in the dentate gyrus is amplified during elevated cognitive demands

    Charlotte CM Castillon, Shintaro Otsuka ... Anis Contractor
    Selective engagement of suprapyramidal dentate gyrus neurons during a high-demand pattern separation task reveals blade-specific circuit engagement for enhancing mnemonic discrimination.
    1. Cell Biology

    Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis

    Changle Zhao, Yongxun Chen ... Jing Wei
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite development

    Pascale Pescher, Thibaut Douché ... Gerald F Späth
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    The role of MICOS in organizing mitochondrial cristae in malaria parasites

    Silvia Tassan-Lugrezin, Irina Bregy ... Laura van Niftrik
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging mouse neurons

    Mofida Abdelmageed, Premkumar Palanisamy ... Anirban Paul
    Progressive DNA polymerase kappa relocalization in aging neurons associates with increased DNA damage and identifies a novel cell type- and activity-dependent role in neuronal genome maintenance.