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Deep3DSIM enables super-resolution imaging >130 µm into complex tissues of fixed and live specimens in an upright configuration, allowing sample manipulation, as well as rapid refocusing without the need to move the specimen or objective lens.

An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle transport.

While the genes involved in craniofacial development are highly conserved between the fat-tailed dunnart and mouse, their cis-regulatory elements show significant divergence and appear to reflect species-specific developmental processes.

In healthy volunteers, negative expectations exert stronger and longer-lasting effects on pain than positive expectations, consistent with a better-safe-than-sorry account of placebo and nocebo effects.

A survey of reasoning behaviour in medical large language models uncovers emerging trends, highlights open challenges, and introduces theoretical frameworks that enhance reasoning behaviour transparency, ultimately fostering greater trust among clinicians, developers, and patients in their deployment.

Learning new navigation or memory skills engages flexible brain network dynamics without altering gray matter, white matter, or hippocampal structure.

Optical tweezers are used to gain mechanistic insight in the mechanism of inhibition of three distinct compounds being developed as antibiotics against Mycobacterium tuberculosis.