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    1. Neuroscience

    A comprehensive mechanosensory connectome reveals a somatotopically organized neural circuit architecture controlling stimulus-aimed grooming of the Drosophila head

    Steven A Calle-Schuler, Alexis E Santana-Cruz ... Andrew M Seeds
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers

    Richard C Centore, Luis MM Soares ... Steven F Bellon
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Computational and Systems Biology
    2. Cancer Biology

    Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML

    Jessica Whittle, Stefan Meyer ... Mudassar Iqbal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Regulation of sensorimotor serial learning in speech production by motor compensation rather than sensory error

    Yuhan Lu, Xiaowei Tang ... Xing Tian
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    DNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2 and -3

    Crystal R Noell, Tzu-Chen Ma ... William O Hancock
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Glycolysis-dependent Sulfur Metabolism Orchestrates Morphological Plasticity and Virulence in Fungi

    Dhrumi Shah, Nikita Rewatkar ... Sriram Varahan
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Stem Cells and Regenerative Medicine

    Rejuvenation-Responsive and Senolytic-Sensitive Muscle Stem Cells Unveiled by CD200 and CD63 in Geriatric Muscle

    Ye Lynne Kim, Young-Woo Jo ... Young-Yun Kong
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    A Titin Missense Variant Causes Atrial Fibrillation

    Mahmud Arif Pavel, Hanna Chen ... Dawood Darbar
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Neuroscience

    Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila

    Jayati Gera, Marishia Agard ... Meet Zandawala
    A multi-pronged approach reveals that ion transport peptide neuropeptide acts through the guanylate cyclase receptor Gyc76C to coordinate osmotic and metabolic homeostasis across multiple tissues in Drosophila.
    1. Cell Biology

    Calcium transfer from the ER to other organelles for optimal signaling in Toxoplasma gondii

    Zhu-Hong Li, Beejan Asady ... Silvia NJ Moreno
    In Toxoplasma gondii, SERCA-driven ER Ca²⁺ uptake sustains homeostasis and enables redistribution to mitochondria and other organelles, highlighting the ER as a central hub in parasite Ca²⁺ signaling and infection.
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