Browse our latest research

Page 29 of 1,836
    1. Neuroscience

    Size tuning of neural response variability in laminar circuits of macaque primary visual cortex

    Lauri Nurminen, Maryam Bijanzadeh, Alessandra Angelucci
    The trial-to-trial variability of neuronal responses and the correlated response variability among neurons are modulated by visual stimulus size in a manner that depends on cortical layer, suggesting multiple circuits and mechanisms as the source of variability.
    1. Cell Biology
    2. Genetics and Genomics

    Non-visual light modulates behavioral memory and gene expression in Caenorhabditis elegans

    Zhijian Ji, Bingying Wang ... Dengke K Ma
    Visible light engages a non-visual, bZIP-dependent transcriptional pathway in peripheral tissues that communicates with the nervous system to shape behavioral plasticity and memory, enabling optogenetic-like gene control without photoreceptors.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Neuroscience

    Transsaccadic working memory in healthy ageing and neurodegenerative disease

    Sijia Zhao, Thomas Parr ... Masud Husain
    Saccades selectively disrupt spatial but not colour memory, and while transsaccadic updating remains resilient to ageing and neurodegeneration, individual drawing deficits arise from impaired initial encoding and memory decay.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Synthetic gene circuits that selectively target RAS-driven cancers

    Gabriel Valentin Senn, Leon Nissen, Yaakov Benenson
    Design and integration of various biomolecular sensors for over-activated rat sarcoma (RAS) created synthetic gene circuits that distinguish mutant versus wild-type signaling and express a therapeutic protein to kill RAS-driven cancer cells.
    1. Neuroscience

    Ventral Hippocampal Temporoammonic and Schaffer Collateral Pathways Differentially Control Fear- and Anxiety-Related Behaviors

    Maltesh Kambali, Muxiao Wang ... Uwe Rudolph
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Inverted encoding of neural responses to audiovisual stimuli reveals super-additive multisensory enhancement

    Zak Buhmann, Amanda K Robinson ... Reuben Rideaux
    A multivariate analysis of electroencephalography activity reveals super-additive enhancements to the neural encoding of audiovisual stimuli, providing new insights into how the brain integrates multisensory information to optimise spatial localisation.
    1. Structural Biology and Molecular Biophysics

    Protein-induced membrane strain drives supercomplex formation

    Maximilian C Pöverlein, Alexander Jussupow ... Ville RI Kaila
    Respiratory supercomplex formation relieves molecular strain of mitochondrial membranes and reshapes global protein motions, linking membrane reorganization to respiratory function.
    1. Neuroscience

    Dynamics of mesoscale brain network during visual discrimination learning revealed by chronic, large-scale single-unit recording

    Tian-Yi Wang, Chengcong Feng ... Zhengtuo Zhao
    During the acquisition of correct rejection response, rankings of functional connection separated for cortical and subcortical regions, which is predictive of the peak timing of visual information encoding across the network.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains

    Caroline Kikawa, Andrea N Loes ... Jesse D Bloom
    High-throughput measurement of neutralization titers using a new sequencing-based assay can help explain which seasonal influenza strains spread in the human population.