Browse our latest research

Page 29 of 1,892
    1. Cell Biology
    2. Physics of Living Systems

    Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

    Daniel Haertter, Lara Hauke ... Christoph F Schmidt
    A non-monotonic force–velocity relationship in cardiac sarcomeres causes dynamic instability, leading to stochastic heterogeneity in contracting cardiomyocytes, which can have a protective function.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Acyl carrier protein is essential for apicoplast biogenesis in malaria parasites independent of fatty acid synthesis

    Sage WR Geher, Seyi Falekun ... Paul A Sigala
    Malaria parasites have evolved a noncanonical function for the apicoplast acyl carrier protein in stabilizing pyruvate kinase II, a metabolic hub essential for isoprenoid synthesis and parasite survival.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    +Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability

    Darren Wethington, Saeed Ahmad ... Jayajit Das
    Stochastic fluctuations play an important role in the MCMV-induced NK cell clonal expansion that ultimately gives rise to memory NK cells.
    1. Neuroscience

    Auditory cortical feedback signals are modulated during songbird courtship

    Caleb Jones, Jesse H Goldberg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Plant Biology
    2. Evolutionary Biology

    Adaptation of an herbivorous arthropod to green tea plants by overcoming catechin defenses

    Naoki Takeda, Brendan Abiskaroon ... Takeshi Suzuki
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Evolutionary Biology
    2. Genetics and Genomics

    Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci

    Michele Marconcini, Steeve Cruchet ... Richard Benton
    Selection of animal populations and of cultured cells provides complementary datasets to identify candidate genes involved in conferring resistance to a natural insecticide.
    1. Cancer Biology

    Nerve injury-induced protein 2 preserves lysosomal membrane integrity to suppress ferroptosis

    Jin Zhang, Miranda Bustamante ... Xinbin Chen
    Revealing a role for NINJ2 in maintaining lysosomal homeostasis and preventing ferroptosis, laying the foundation for the development of cancer therapeutics targeting NINJ2.
    1. Neuroscience

    PRRT2 as an auxiliary regulator of Nav channel slow inactivation

    Bin Lu, Qi-Wu Xu ... Zhi-Qi Xiong
    PRRT2 is identified as a conserved regulator of sodium channel slow inactivation that helps protect the neurons from excessive excitability.
    1. Cell Biology
    2. Neuroscience

    A quantitative portrait of habituation in Stentor coeruleus

    Tejas Ramdas, Nhi Doan ... Samuel J Gershman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Topological structure in human spatial representation revealed through drawing

    Mahwish Kittur, Agnes Zhang ... Sami R Yousif
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing