Dopamine and GABA neurons in the ventral tegmental area encode short-term memory in the T-maze task, which cannot be explained by reward-related processes, motivated behavior, or motor-related activities.
Mina O Seedhom, Devin Dersh ... Jonathan W Yewdell
Quantitative protein and ribosome 'accounting' in T cells highlights a gap in our understanding of how activated T cells sufficiently replicate their proteome during rapid cell division driven by infection.
Andrea Salazar Lázaro, Thorsten Trimbuch ... Christian Rosenmund
Structure–function studies on the synaptic vesicle release protein syntaxin-1 identified structural motifs on the surface of the SNARE complex controlling vesicle priming and spontaneous release unique for synaptic signaling.
Brain-wide activation patterns reveal the distinct and shared neurophysiological impacts of ketamine and isoflurane, highlighting key nuclei involved in the modulation of general anesthesia.
Visuo-auditory associative memories in the neocortex are formed through cholecystokinin-mediated heterosynaptic plasticity, primarily involving entorhinal cortex projections to the auditory cortex, highlighting intricate neural dynamics in multisensory memory processing.
Martin Wohlwend, Pirkka-Pekka Laurila ... Johan Auwerx
CERS1 reduction in aging skeletal muscle contributes to impaired muscle function, myogenesis and increases inflammation and fibrosis, highlighting the significance of very long chain ceramides in age-related muscle homeostasis.
The SARS-CoV-2 Spike proteins demonstrate in vivo cellular tropism, ascertain targets within human mononuclear cells, and provide insights into their functional consequences, thereby enhancing comprehension of their impact on humans.
There are many fine-scale scene-selective areas within the visual system, beyond the occipital, temporal, and medial place areas, whose function may be key to performing complex tasks in dynamic environments.
