Browse our latest research

A microbiome metabolite alleviates liver steatosis and inflammation, and shows its potential as a therapeutic modality for non-alcoholic fatty liver disease.

Investigation of how cells rewire their transcriptional programs during transition from mitotic to meiotic cell fate reveals a two-pronged mechanism for inactivating a key mitotic transcription factor.

Volatile compounds from microbes and food alter epigenetic states by inhibiting histone deacetylases and alter gene expression, slow degeneration in Huntington’s model flies, and slow proliferation of a neuroblastoma cell line.

The gain of transposable elements in yeast hybrids does not scale with genetic divergence levels and is most impacted by structural variations and multiple aspects of individual hybrid genetic backgrounds.

SNAP25 disease mutations within the synaptotagmin interface impair vesicle priming and cause uncontrolled spontaneous release due to enhanced SNARE:SNARE interactions, whereas a mutation within the SNARE-bundle increases the fusion energy barrier.

A novel pan-neuronal antibody has revealed the organization of the nerve net controlling all behavior in the simple cnidarian Hydra.

Cells utilize a membrane-mediated mechanism for mechanosensation, which involves the disruption of lipid rafts and a signal relayed to an ion channel.

A novel network information framework quantifies muscle interactions, characterises their task-relevance, and identifies networks of muscles with similar and complementary functional roles.