Augustine Xiaoran Yuan, Jennifer Colonell ... Timothy D Harris
Neurons can be tracked in mice implanted with Neuropixels 2.0 probes for up to 8 weeks using visual receptive fields to score tracking in the absence of reference data.
Rajdeep Banerjee, Thomas J Meyer ... David D Roberts
Increased extramedullary erythropoiesis in spleen compensates for the elevated turnover of red blood cells in mice lacking CD47, but extramedullary erythropoiesis is suppressed in mice lacking the CD47 ligand thrombospondin-1.
Ladan Shahshahani, Maedbh King ... Jörn Diedrichsen
The human cerebellum shows fMRI activity for many tasks – however, the inputs from the neocortex are upregulated in a task-dependent manner when cerebellar computation is required.
When exposed to high-dose ionizing radiation, tardigrades undergo extensive DNA damage, like humans, but cope by stimulating expression of DNA repair proteins and of TDR1, a novel tardigrade-specific DNA-binding protein.
Indoxyl sulfate, a key uremic toxin in chronic kidney disease (CKD), induces trained immunity in monocytes via crosstalk between aryl hydrocarbon receptor (AhR)-dependent epigenetic reprogramming by enhancement of the arachidonic acid pathway and AhR-independent metabolic rewiring.
A prognostic model constructed based on RNA-sequencing and clinical specimens analyses reveals VCAN, C1QB, and CD3G could be key factors in modulating tumor microenviornment of DLBCL.
