Browse our latest research

Experiments including cell and animal models investigate the molecular mechanisms underlying the regulation of homeostasis and function of monocytes.

Doves improve their wingbeat efficacy without elevating maximum pectoralis power by angling their wings mid-downstroke to efficiently generate aerodynamic force while simultaneously tensioning the supracoracoideus tendon to assist the upstroke.

ScRNA-seq of diverse pheochromocytoma patients reveals distinct microenvironment characteristics and supports an informative molecular classification system.

A massively parallel reporter assay, mSTARR-seq, reveals widespread DNA methylation-environment interactions across the genome, prioritizing CpG sites identified in epigenome-wide association studies that may be most relevant to biological embedding.

Comparing tissue-specific plasma cfDNA concentration with cellular turnover rates reveals that less than 10% of dying cells' DNA reaches plasma, highlighting significant local clearance mechanisms and suggesitng approaches to enhance liquid biopsy sensitivity.

Behavioral and neural analyses unravel the angular gyrus’ key role in the prioritization of integrated narratives in memory and the orchestration of theta-frequency reconfigurations underpinning the process of memory integration.

Chimeric RNAs are widely distributed spatiotemporally during human retinal development and have important regulatory functions, such as silencing of CTNNBIP1-CLSTN1 biasing the progenitor cells toward the RPE cell fate at the expense of neural retinal cell fates.

A hitherto unknown role of Piezo1 mechanosensors in chemotactic migration of human T cells is identified, linking focal adhesion formation to integrin recruitment.

A genetically encoded fluorescent biosensor reveals temporally resolved changes to aspartate concentration during genetic, pharmacological, and nutritional manipulations.