Alexander N Kapustin, Sofia Serena Tsakali ... Catherine M Shanahan
Fibronectin triggers secretion of extracellular vesicles carrying collagen VI that regulate smooth muscle cell adhesion and migration during vascular repair and atherogenesis.
A biochemical and bioinformatics approach shows how T6SS immunity proteins bind to and neutralize a range of non-cognate effectors, which is critical for promoting bacterial fitness in mixed-strain environments.
Rapamycin, competing with other rapalogs, activates TRPM8 via directly binding to a novel binding site, which results in providing new insights into the mechanisms of TRPM8 activation.
Neurons selective to running trajectories in the rat anterior cingulate cortex are reactivated during observation and interact with hippocampal replay to guide subsequent spatial navigation.
Functional connectivity mapping reveals sparse, specific, and largely complementary cortical innervation of individual striatal medium spiny neurons within overlapping and loosely topographical projections from the barrel cortex.
Antara Sengupta, Soujanya Vinayagamurthy ... Shantanu Chowdhury
Telomere length controls hTERT expression by modulating TRF2 distribution and PRC2-mediated repression, highlighting a self-regulatory mechanism in cancer.
