Associative plasticity of proximal and distal granule cell inputs to Purkinje cells enables time dependent association of information from local and distant receptive fields.
Uncovering pharyngeal sour taste receptors in Drosophila melanogaster reveals a novel mechanism for detecting ingested carboxylic acids, expanding understanding of how insects internally sense and respond to appetitive tastants.
Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
12 new class IIb microcins have been structurally identified, phylogenetically assessed, and functionally tested for their antimicrobial activity, increasing the total number of these bacteriocins to 17.
Somatic mutations frequently disrupt cleavage and polyadenylation signals in tumour suppressor genes in human cancers, likely contributing to tumour progression.
Time-related sequential activities in prefrontal cortex exhibit stable coding over weeks, while representations of other variables are dynamic, suggesting that neural sequences are consisted of unique group of neurons.
Imran S Khan, Christopher Molina ... Dean Sheppard
Reduced lung myofibroblast proliferation is a unifying feature in multiple models of developmental emphysema and inhibition of myofibroblast proliferation is sufficient to cause this pathology.
Amanda Mixon Blackwell, Yasaman Jami-Alahmadi ... Paul A Sigala
Plasmodium parasites have repurposed the heme oxygenase scaffold from its canonical heme-degrading function to fulfill an essential and adaptive role in gene expression within the apicoplast organelle.
