Browse our latest research

Page 37 of 1,757
    1. Neuroscience

    A ventral hippocampal-lateral septum pathway regulates social novelty preference

    Maha Rashid, Sarah Thomas ... Malavika Murugan
    Projection-specific optogenetic and chemogenetic experiments reveal a hippocampal-lateral septal pathway that potentially acts via the ventral tegmental area to regulate social novelty preference behaviors.
    1. Cancer Biology

    Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab-resistant HER2-positive breast cancer

    Yijia Hua, Ningjun Duan ... Yongmei Yin
    Targeting cysteine metabolism could provide novel strategies for treating trastuzumab-resistant HER2-positive breast cancer.
    1. Cell Biology

    Glucose-stimulated KIF5B-driven microtubule sliding organizes microtubule networks in pancreatic β cells

    Kai M Bracey, Margret Fye ... Irina Kaverina
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice

    Atsuko Kageyama, Narumi Ogonuki ... Junya Ito
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during development

    Saman Hussain, Katherine Pinter ... Katie S Kindt
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains

    Caroline Kikawa, Andrea N Loes ... Jesse D Bloom
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics

    Confirmation of HLA-II associations with TB susceptibility in admixed African samples

    Dayna Adrienne Croock, Yolandi Swart ... Caitlin Uren
    A local-ancestry-aware association model identified a suggestive association peak within the HLA class II region linked to TB in a complex, highly admixed Southern African population.
    1. Neuroscience

    The role of GABA in semantic memory and its neuroplasticity

    JeYoung Jung, Steve Williams, Matthew A Lambon Ralph
    GABAergic inhibition in the anterior temporal lobe shapes semantic memory and its neuroplasticity through a non-linear relationship, revealing a neurochemical basis for individual differences.
    1. Computational and Systems Biology

    Pathway activation model for personalized prediction of drug synergy

    Quang Thinh Trac, Yue Huang ... Trung Nghia Vu
    Drug synergy Interaction Prediction improves personalized drug synergy prediction by utilizing drug-specific pathway activation scores to predict personalized drug synergy and reveals mechanistic pathways underlying synergistic effects.
    1. Cell Biology

    HNF4α-TET2-FBP1 axis contributes to gluconeogenesis and type 2 diabetes

    Hongchen Li, Xinchao Zhang ... Yanping Xu
    Functional analyses reveal the HNF4α-TET2-FBP1 axis as a critical regulator of gluconeogenesis, type 2 diabetes (T2D) progression, and metformin’s therapeutic effects, which proposes TET2 as a promising therapeutic target for T2D.