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    1. Neuroscience

    Single molecule counting detects low-copy glycine receptors in hippocampal and striatal synapses

    Serena Camuso, Yana Vella ... Christian G Specht
    Synapses in the forebrain were thought of as purely GABAergic, yet they contain minute numbers of glycine receptors, often in the single digits.
    1. Genetics and Genomics

    Visible traits demonstrate that crispant founder mice can be used for phenotypic assessment

    Rebekah Tillotson, Marina Gertsenstein ... Monica J Justice
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Neuroscience

    Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability

    Simone Carneiro-Nascimento, Chao Wei ... Dan Levy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Patient-Specific Midbrain Organoids with CRISPR Correction Reveal Disease Mechanisms and Enable Therapeutic Evaluation in Neuronopathic Gaucher Disease

    Yi Lin, Benjamin Liou ... Ying Sun
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Medicine

    The inactivation of DHHC7 in mouse liver promotes diet-induced obesity through a hepatic Prg4–GPR146 axis

    Yingmin Sun, Ying Liu ... Bing Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Trehalose metabolism regulates transcriptional control of muscle development in lepidopteran insects

    Sharada Mohite, Tanaji Devkate ... Rakesh Shamsunder Joshi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Human receptive endometrial assembloid for deciphering the implantation window

    Yu Zhang, Rusong Zhao ... Han Zhao
    Revised
    Reviewed Preprint v4
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Trial-level Representational Similarity Analysis

    Shenyang Huang, Cortney M Howard ... Simon W Davis
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Mixture discrimination training induces durable and generalizable olfactory learning independent of odorant structure and concentration

    Xiaoyue Chang, Huibang Tan ... Wen Zhou
    Mixture discrimination training induces durable, transferable olfactory learning, highlighting mixture configural odor quality as a distinct attribute supported by different plasticity mechanisms than chirality or concentration and offering a promising leverage point for olfactory rehabilitation.
    1. Immunology and Inflammation

    TGF-β drives the conversion of conventional NK cells into uterine tissue-resident NK cells to support murine pregnancy

    Josselyn D Barahona, Liping Yang ... Wayne M Yokoyama
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
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