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CryoEM reveals the structure of a two-component archaeal S-layer, which sheds new light on archaeal cell biology.

A neural circuit model reveals how biological brains may implement rapid learning and navigation in complex spaces.

Caffeine modulates the genetic risk for cardiovascular disease through changes in target gene expression, likely due to regulation of transcription factor binding.

EZH2 is regulated by a K20-methylation dependent proteolysis and this proteolysis process is negatively controlled by AKT-mediated S21 phosphorylation to establish a methylation-phosphorylation switch to control the PRC2 activity and hematopoiesis.

An experimental animal model provides further insights into the host and viral mechanisms underlying airborne transmission of SARS-CoV-2.

Prompt contact tracing (testing at the beginning instead of at the end of isolation period) of individuals with COVID-19 in the community reduces delays in contact tracing, increases identification of source of infection, and reduces transmission rates in educational settings.

Physical interactions are a minor contributor to the correlations in evolutionary rate over time that are observed between co-functional proteins.

A useful single-cell resource provides the prenatal macaque different cell types’ gene expression profiles in the parietal cerebral cortex lobe.

A giant multifunctional protein complex mediates mating-type recognition through a non-ligand–receptor mechanism in a multisexual species.