Browse our latest research

Page 431 of 1,751
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Neural circuit-wide analysis of changes to gene expression during deafening-induced birdsong destabilization

    Bradley M Colquitt, Kelly Li ... Michael S Brainard
    Large-scale gene expression analysis of the songbird brain identifies the molecular and cellular features of vocal motor circuits that are altered by the loss of hearing.
    1. Stem Cells and Regenerative Medicine

    Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity

    Claudia Dominici, Oscar D Villarreal ... Stéphane Richard
    Inhibition of type I PRMTs increases the proliferation capabilities of MuSCs with altered cellular metabolism, while maintaining their stem-like properties such as self-renewal and engraftment potential.
    1. Microbiology and Infectious Disease

    The large GTPase Sey1/atlastin mediates lipid droplet- and FadL-dependent intracellular fatty acid metabolism of Legionella pneumophila

    Dario Hüsler, Pia Stauffer ... Hubert Hilbi
    Intracellular growth of the bacterial pathogen Legionella pneumophila in the amoeba Dictyostelium discoideum implicates a bacterial fatty acid transporter as well as dynamic interactions of the distinct membrane-bound replication compartment with host cell lipid droplets.
    1. Neuroscience

    Neural dynamics underlying self-control in the primate subthalamic nucleus

    Benjamin Pasquereau, Robert S Turner
    Cost–benefit integration between the desirability of the expected reward and the imposed delay to delivery is supported by STN signals that dynamically combined both reward-related attributes to form a single integrated value estimate along an antero-posterior axis in this nucleus.
    1. Neuroscience

    Using light and X-ray scattering to untangle complex neuronal orientations and validate diffusion MRI

    Miriam Menzel, David Gräßel ... Marios Georgiadis
    Light and X-ray scattering on the same primate and human brain samples cross-validate each other and enable accurate mapping of axonal trajectories in regions with uni- and multi-directional nerve fibers, which can be used to validate diffusion MRI.
    1. Neuroscience

    Changing the incentive structure of social media platforms to halt the spread of misinformation

    Laura K Globig, Nora Holtz, Tali Sharot
    Offering users reaction buttons that convey reliability (e.g., ‘trust’, ‘distrust’) increases discernment and significantly reduces the spread of misinformation on a social media platform.
    1. Ecology
    2. Evolutionary Biology

    Metabolic consequences of various fruit-based diets in a generalist insect species

    Laure Olazcuaga, Raymonde Baltenweck ... Julien Foucaud
    Metabolomic analyses indicate that diet generalism may stem from a neutral metabolic response to different chemistries, rather than from an accumulation of specific adaptations.
    1. Genetics and Genomics

    Mec1-independent activation of the Rad53 checkpoint kinase revealed by quantitative analysis of protein localization dynamics

    Brandon Ho, Ethan J Sanford ... Grant W Brown
    Retrograde signaling activates the Rad53 checkpoint kinase independently of the canonical DNA replication stress response.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Endoparasitoid lifestyle promotes endogenization and domestication of dsDNA viruses

    Benjamin Guinet, David Lepetit ... Julien Varaldi
    The propensity to endogenize and domesticate dsDNA viruses depends on lifestyle in Hymenoptera.
    1. Medicine

    Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain

    Federico Salas-Lucia, Csaba Fekete ... Antonio C Bianco
    T3 is taken up by axonal termini and is retrogradely transported into endosomal vesicles to the cell nucleus, where it regulates gene expression.