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    1. Neuroscience

    Age-related changes in ‘cortical’ 1/f dynamics are linked to cardiac activity

    Fabian Schmidt, Sarah K Danböck ... Nathan Weisz
    Age-related differences in cortical aperiodic signals can be driven by cardiac influences, emphasizing the need to control for cardiac contributions in studies interpreting cortically measured aperiodic dynamics.
    1. Chromosomes and Gene Expression

    Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression

    Yoshinori Kohwi, Xianrong Wong ... Terumi Kohwi-Shigematsu
    Modified ChIP-seq and 4C-seq approaches, using urea-purified crosslinked chromatin, uncovered a two-tiered chromatin organization mediated by SATB1 that is linked to gene expression.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

    Shivraj M Yabaji, Vadim Zhernovkov ... Igor Kramnik
    Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.
    1. Neuroscience

    Balancing safety and efficiency in human decision-making

    Pranav Mahajan, Shuangyi Tong ... Ben Seymour
    A separate fear system, flexibly gated by outcome uncertainty, guides decision-making to be both safe and efficient during exploration.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Understanding the global rise of artemisinin resistance: Insights from over 100,000 Plasmodium falciparum samples

    Andrew J Balmer, Nina FD White ... Cristina Ariani
    Spatiotemporal analysis of global kelch13 surveillance data reveals that artemisinin resistance is increasing in East Africa, mirroring patterns previously observed in Southeast Asia.
    1. Microbiology and Infectious Disease
    2. Ecology

    BuzzWatch: Uncovering Multi-scale Temporal Patterns in Mosquito Behavior Through Continuous Long-term Monitoring

    Théo Maire, Zhong Wan ... Felix JH Hol
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans

    Marilina Raices, Fabiola Balmir ... Judith L Yanowitz
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability

    Darren Wethington, Saeed Ahmad ... Jayajit Das
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Orco regulates the circadian activity of pheromone-sensitive olfactory receptor neurons in hawkmoths

    Aditi Vijayan, Mauro Forlino ... Monika Stengl
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Epidemiology and Global Health

    Using step selection functions to analyse human mobility using telemetry data in infectious disease epidemiology: a case study of leptospirosis

    Pablo Ruiz Cuenca, Fabio Neves Souza ... Emanuele Giorgi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
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