Transcriptomic heterogeneity in infective-stage surface proteins of Trypanosoma cruzi, particularly trans-sialidase-like superfamily members, suggests distinct expression profiles among individual parasites that may enhance immune evasion and infection adaptability.
Dysregulated exocytosis of bis(monoacylglycerol)phosphate (BMP)-enriched extracellular vesicles driven by pathogenic LRRK2 activity supports elevated urinary BMP levels and its use as a biomarker for Parkinson's disease.