Browse our latest research

Page 53 of 1,889
    1. Cancer Biology

    CDK4 or CDK6 upregulation induces DNA replication stress and genomic instability to cause EGFR targeted therapy resistance in lung cancer

    Beatrice Gini, Philippe Gui ... Collin M Blakely
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation

    ImPaqT, a Golden Gate-based immunological toolkit for zebrafish transgenesis

    Saskia Hurst, Christiane Dimmler, Mark R Cronan
    ImPaqT is an immune toolkit that enables modular and expandable cloning of zebrafish transgenes using Golden Gate-based cloning techniques.
    1. Genetics and Genomics
    2. Neuroscience

    Acute opioid responses are modulated by dynamic interactions of Oprm1 and Fgf12

    Paige M Lemen, Yanning Zuo ... Hao Chen
    A time-dependent genetic interaction between the µ opioid receptor and genes drives early morphine responses in mice, highlighting pathways linked to human substance use disorder.
    1. Cell Biology
    2. Cancer Biology

    Adaptive plasticity of aspartate metabolism in succinate dehydrogenase-deficient cancer cells

    David Sokolov, Eric Zheng ... Lucas B Sullivan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Multi-area activity in mouse motor cortex associated with one- and two-handed oromanual dexterity

    John M Barrett, Joshua I Glaser ... Gordon MG Shepherd
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    CellCover defines marker gene panels capturing developmental progression in neocortical neural stem cell identity

    Lanlan Ji, An Wang ... Donald Geman
    In contrast to differential expression-based methods, which evaluate and select individual marker genes, CellCover identifies panels of genes that function together to define cell types.
    1. Neuroscience

    Behavioral signatures of post-decisional attention in preferential choice

    Ariel Zylberberg, Ian Krajbich, Michael N Shadlen
    Gaze patterns during value-based choice may reflect post-decision processes rather than a direct causal influence of attention on preference formation.
    1. Medicine

    Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

    Lu Xiao, Lu Li ... Jia Xiao
    MgIG directly targets HSD11B1 to alleviate alcohol-associated liver disease by suppressing the HSD11B1–SREBP2–IDI1 pathway, thereby reducing hepatic steatosis, inflammation, and apoptosis.
    1. Neuroscience

    Excitatory cholecystokinin neurons in the CA3 area regulate the navigation learning and neuroplasticity

    Fengwen Huang, Abdul Baset, Stephen Temitayo Bello
    Cholecystokinin release from CA3 inputs to CA1 links local excitatory circuitry to hippocampal plasticity and spatial memory.