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    1. Cancer Biology
    2. Computational and Systems Biology

    Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML

    Jessica Whittle, Stefan Meyer ... Mudassar Iqbal
    A comprehensive single-cell atlas of AML uncovers regulatory networks and age-dependent molecular differences to advance the understanding of disease mechanisms and enable subtype-specific therapeutic strategies.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Heterogeneous associations of polygenic indices of 35 traits with mortality: a register-linked population-based follow-up study

    Hannu Lahtinen, Jaakko Kaprio ... Pekka Martikainen
    Polygenic indices related to the best-established social, psychological, and behavioural mortality risk phenotypes had the strongest associations with mortality.
    1. Developmental Biology
    2. Genetics and Genomics

    PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development

    Julia Raulino Lima, Nicha Ungvijanpunya ... Jian Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Divergent spatial codes in retrosplenial cortex and hippocampus support multi-scale representation of complex environments

    Célia Laurent, Nada El Mahmoudi ... Pierre-Yves Jacob
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    RHODOPSIN 7: An ancient non-retinal photoreceptor for contrast vision, darkness detection, and circadian regulation

    Valentina Kirsch, Nils Reinhard ... Pingkalai R Senthilan
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Evolutionary Biology

    Recombination shapes the diversification of the wtf meiotic drivers

    Yan Wang, Hao Xu ... Guan-Zhu Han
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Backward conditioning reveals flexibility in infralimbic cortex inhibitory memories

    Nura W Lingawi, Billy Chieng ... Vincent Laurent
    Optogenetic stimulation of the infralimbic cortex reveals properties of local inhibitory memories.
    1. Neuroscience

    Compressed sensing-based approach identifies modular neural circuitry driving learned pathogen avoidance

    Timothy Hallacy, Abdullah Yonar ... Sharad Ramanathan
    An efficient neural screening approach rapidly identifies circuit modules governing distinct behavioral transitions in response to pathogen exposure.
    1. Developmental Biology

    map3k1 is required for spatial restriction of progenitor differentiation in planarians

    Bryanna Isela-Inez Canales, Hunter O King, Peter W Reddien
    map3k1 inhibits progenitor differentiation until suitable positional cues are acquired as a mechanism of pattern formation.
    1. Neuroscience

    Sense of control buffers against stress

    Jennifer C Fielder, Jinyu Shi ... Nikolaus Steinbeis
    A novel behavioural task that measures and manipulates subjective control in humans reveals that experimentally heightened feelings of control buffer against the negative impact of subsequent stress.
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