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    1. Genetics and Genomics
    2. Cancer Biology

    Early Diagnosis and Prognostic Prediction of Colorectal Cancer through Plasma Methylation Regions

    Lingqin Zhu, Lang Yang ... Jianqiu Sheng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    Loss of the s2U tRNA modification induces antibiotic tolerance and is linked to changes in ribosomal protein expression

    Katherine L Cotten, Abigail McShane ... Kimberly M Davis
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Biochemistry and Chemical Biology

    A simplified and highly efficient cell-free protein synthesis system for prokaryotes

    Xianshengjie Lang, Changbin Zhang ... Wenfei Li
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

    Roberta Carloni, Tadhg Devlin ... Robin C Allshire
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Epidemiology and Global Health

    Estimating probabilities of malaria importation in southern Mozambique through P. falciparum genomics and mobility patterns

    Arnau Pujol, Arlindo Chidimatembue ... Alfredo Mayor
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Evolutionary Biology
    2. Neuroscience

    A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma

    Mireia Rovira, Giuliano Ferrero ... Valerie Wittamer
    The zebrafish brain combines a conserved heterogeneity of immune cells with a unique dendritic cell-like population.
    1. Physics of Living Systems

    Advantageous and disadvantageous inequality aversion can be taught through learning of others’ preferences

    Shen Zhang, Oriel FeldmanHall ... A Ross Otto
    Like disadvantageous inequity aversion, advantageous inequity aversion can be learned by observing another’s fairness preferences.
    1. Genetics and Genomics

    Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome

    Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
    Cross-species functional genomics identify ribosomal protein genes as key regulators of cardiomyocyte proliferation and heart development, implicating them as candidate modifiers for HLHS and revealing new avenues for therapeutic discovery.
    1. Cell Biology
    2. Developmental Biology

    The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice

    Atsuko Kageyama, Narumi Ogonuki ... Junya Ito
    The zinc transporter Slc39a10/Zip10 is important for zinc homeostasis during fertilization and embryonic development in mice.
    1. Biochemistry and Chemical Biology

    General trends in the calnexin-dependent expression and pharmacological rescue of clinical CFTR variants

    Austin Tedman, John A Olson III ... Jonathan P Schlebach
    Combining deep mutational scanning with CRISPR, interactome measurements, and electrophysiology reveals nuanced effects of the lectin chaperone calnexin on the pharmacological properties of 232 cystic fibrosis variants.
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