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    1. Neuroscience

    Brain-derived estrogens facilitate male-typical behaviors by potentiating androgen receptor signaling in medaka

    Yuji Nishiike, Shizuku Maki ... Kataaki Okubo
    Estrogens produced in the teleost brain increase neural sensitivity to testicular androgens by directly stimulating androgen receptor transcription, thereby eliciting male-typical behaviors.
    1. Microbiology and Infectious Disease

    ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis

    Tejan Lodhiya, Aseem Palande ... Raju Mukherjee
    Multiomics and biochemical studies reveal that excess ATP levels, and not ROS, is the dominant driver for antibiotic cidality in Mycobacterium smegmatis.
    1. Neuroscience

    Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals

    Calum Stewart, T Adam Liddle ... Tyler J Stevenson
    Transcriptomic and genomic mutations reveal the mechanistic basis of timing seasonal life history transitions.
    1. Developmental Biology
    2. Neuroscience

    Comparative developmental transcriptomics of Drosophila mushroom body neurons highlights the mevalonate pathway as a regulator of axon growth

    Lora Fahdan, Hagar Meltzer ... Oren Schuldiner
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Neuroscience

    Motor unit mechanisms of speed control in mouse locomotion

    Kyle Thomas, Rhuna Gibbs ... Samuel J Sober
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Dissociable neural substrates of integration and segregation in exogenous attention

    Yu-Jie Chen, Ai-Su Li ... Yang Zhang
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Symmetric brain-liver circuits mediate lateralized regulation of hepatic glucose output

    Zhonglong Wang, Xiangfei Gong ... Hao Xie
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease

    Pathogen-Phage Geomapping to Overcome Resistance

    Camilla Do, Keiko C Salazar ... Anthony W Maresso
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    A geometric shape regularity effect in the human brain

    Mathias Sablé-Meyer, Lucas Benjamin ... Stanislas Dehaene
    fMRI and MEG results in adults and children show encoding of abstract geometric regularities in dorsal-parietal, temporal, and frontal regions, pointing to a system for symbolic geometric representation in humans.
    1. Cell Biology

    Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

    Atsushi Matsumoto, Akihito Inoko ... Junichi Ikenouchi
    Lipid imbalance triggered by Snail-driven epithelial–mesenchymal transition creates a cholesterol-dependent vulnerability that can be therapeutically targeted to overcome chemoresistance in cancer.
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