Browse our latest research

Page 584 of 1,754
    1. Computational and Systems Biology

    Integrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets

    Zhuang Liu, Letian Zhang ... Ning Xu Landén
    A comprehensive microRNA expression and function landscape of human wounds unraveled miRNAs highly relevant to venous ulcer pathology.
    1. Neuroscience

    Flexible and efficient simulation-based inference for models of decision-making

    Jan Boelts, Jan-Matthis Lueckmann ... Jakob H Macke
    A new machine learning method makes it possible to efficiently identify the parameters of cognitive models using Bayesian inference, even when only model simulations are available.
    1. Cell Biology

    CXCR4high megakaryocytes regulate host-defense immunity against bacterial pathogens

    Jin Wang, Jiayi Xie ... Meng Zhao
    scRNA-seq identified CXCR4high MKs can funtionally regulate host-defense immune response against bacterial infection.
    1. Cell Biology

    Ubiquitination drives COPI priming and Golgi SNARE localization

    Swapneeta S Date, Peng Xu ... Todd R Graham
    The ability of COPI to bind polyubiquitin is a key determinant for SNARE incorporation into intracellular vesicles and for maintenance of a functional Golgi complex.
    1. Cell Biology

    Distinct roles for two Caenorhabditis elegans acid-sensing ion channels in an ultradian clock

    Eva Kaulich, Trae Carroll ... Denise S Walker
    Two acid-sensing members of the degenerin/epithelial sodium channel family play distinct roles in controlling different aspects of rhythmic proton and calcium oscillations in the nematode intestine.
    1. Physics of Living Systems

    Learning to predict target location with turbulent odor plumes

    Nicola Rigolli, Nicodemo Magnoli ... Agnese Seminara
    Intensity of an odor and timing of its detection are complementary attributes of turbulent plumes and enable robust prediction of the location of a distant target.
    1. Stem Cells and Regenerative Medicine

    Generation of functional hepatocytes by forward programming with nuclear receptors

    Rute A Tomaz, Ekaterini D Zacharis ... Ludovic Vallier
    Forward programming of human pluripotent stem cells with a combination of four transcription factors allows the production of functional hepatocytes.
    1. Computational and Systems Biology
    2. Neuroscience

    Information flows from hippocampus to auditory cortex during replay of verbal working memory items

    Vasileios Dimakopoulos, Pierre Mégevand ... Johannes Sarnthein
    Precisely tracking the anatomical sources of neural computations infers functional directed connectivity between hippocampal memory neurons and cortical sensory neurons, it reveals information flowing from cortex to hippocampus during encoding but the reverse direction during maintenance.
    1. Immunology and Inflammation

    Glutamine metabolism modulates chondrocyte inflammatory response

    Manoj Arra, Gaurav Swarnkar ... Yousef Abu-Amer
    Glutamine deprivation reprograms chondrocytes, attenuates inflammation, and such intervention may be protective against joint inflammation.
    1. Cell Biology

    Modular, cascade-like transcriptional program of regeneration in Stentor

    Pranidhi Sood, Athena Lin ... Wallace F Marshall
    Regeneration of single Stentor coeruleus cells is accompanied by a program of gene expression that can be decomposed into distinct modules, showing a cascade-like organization, and involving genes with conserved function in development and cell cycle control.