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Development of a live single-molecule imaging approach to visualize XBP1 mRNAs, which are recruited for translation on the ER and efficiently spliced in the absence of large IRE1α foci.

Activation of TRPV4 induced increases in Ca²⁺ influx, activated CaMKII, enhanced pro-inflammatory NFκB-NLRP3 signaling, and promoted inflammation response, thus contributing to pathological cardiac remodeling.

Pharmacological fMRI study provides evidence that learning from the unexpected presence and absence of pain is mediated by different brain systems.

A landmark-based cross-modality alignment method robust to variation in landmark sets is applied to annotate an EM time series of Caenorhabditis elegans embryonic development as a community resource.

Identification of a novel role for the transcriptional repressor, MAF1, and RNA polymerase III-dependent transcription, in osteoblast differentiation, mineralization, and bone biology.

The COVID-19 pandemic reduced participation in a Spanish population-based breast cancer screening program, especially among regular participants, while other outcomes like recall and cancer detection were not negatively affected by the interruption of screening.

The auditory system adapts to the changing acoustics of reverberant environments by temporally shifting the inhibitory tuning of cortical neurons to reduce the effects of reverberation.

Mycobacterium tuberculosis, which causes tuberculosis, can evolve rapidly in response to new environments by mutating genetic regulators that control multiple genes at once.

Generally recognised as safe GABA-producing L. lactis strains could be considered as future therapeutic agents for the management of visceral pain and the anxious profile of IBS patients.

Streptococcus pyogenes M87 protein unfurls its coiled coil to capture and neutralize the human antimicrobial peptide LL-37.