Browse our latest research

Page 76 of 1,861
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Elucidating the kinetic and thermodynamic insight into regulation of glycolysis by lactate dehydrogenase and its impact on tricarboxylic acid cycle and oxidative phosphorylation in cancer cells

    Siying Zeng, Yuqi Wang ... Xun Hu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Spatially targeted inhibitory rhythms differentially affect neuronal integration

    Drew B Headley, Benjamin Latimer ... Satish S Nair
    Beta and gamma inhibitory rhythms are preferentially tuned to govern synaptic integration in layer 5 pyramidal neurons by differentially modulating responses to inputs targeting distal dendritic and perisomatic compartments.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression

    Jie Lin, Yujian Wen ... Hao Zhu
    Compared with human-specific transcriptional factors, human-specific lncRNAs identified upon human lncRNAs’ orthologs in mammals have greatly evolved DNA-binding sites in archaic and modern humans in genes determining human traits.
    1. Neuroscience

    Readout and delayed transmission of initial afferent V1 activity in decisions about stimulus contrast

    Kieran S Mohr, Simon P Kelly
    Evidence is provided suggesting that aggregate neural activity at an early stage of visual processing (V1) can directly contribute to perceptual decisions in humans.
    1. Structural Biology and Molecular Biophysics

    Insights into substrate binding and utilization by hyaluronan synthase

    Zachery Stephens, Julia Karasinska, Jochen Zimmer
    Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.
    1. Neuroscience

    A hypothalamo-septo-hippocampal circuit for REM sleep-dependent consolidation of social memory

    Tingliang Jian, Wenjun Jin ... Han Qin
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Immunology and Inflammation

    Temporal single-cell analysis reveals age-associated delay in immune resolution after respiratory viral infection

    Yue Wu, Chaofan Li ... Jie Sun
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Interaction hierarchy among Cdv proteins drives recruitment to membrane necks

    Nicola De Franceschi, Alberto Blanch-Jover, Cees Dekker
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules

    Mariam Ahmed Fouad, Christopher S Parry ... John Karanicolas
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Ripply1 and Gsc collectively suppress anterior endoderm differentiation from prechordal plate progenitors

    Tao Cheng, Xiang Liu ... Peng-Fei Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
Newer articles Older articles