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In vivo crosslinking approaches revealed that the edge-strand of Escherichia coli metallopeptidase BepA interacts with an assembly intermediate of β-barrel outer membrane protein LptD on the outer membrane protein translocon for its targeting to degradation or maturation.

The characterization of ancient B19V and HBV genotype A4 viruses circulating during Colonial epidemics provides new insights into the pathogens that were introduced to the Americas after the European colonization.

Modern human diet patterns alter primate behavior and monocyte gene expression leading to monocyte polarization–experimental evidence of the evolutionary mismatch hypothesis.

HiLITR is a molecular reporter of protein localization that enables straightforward, large-scale, fluorescence-activated cell sorting-based discovery of genes that regulate complex cellular processes, such as mitochondrial and ER tail-anchored protein trafficking.

Naturally occurring activity in the developing brain regulates mitochondrial motility such that mitochondria stop at active synapses, which is probably a fundamental process in brain wiring.

Evolutionary game theory identifies reciprocation as a key winning strategy for warring bacteria.

Starfish feed by everting their stomach out of their mouth over prey and, interestingly, this unusual feeding mechanism is inhibited by substances similar to hormones that regulate feeding in humans.

Neural processes for perception and confidence can be separated thanks to computational electroencephalography, thus revealing a neural circuit specific to metacognition.

Prefrontal cortex plays a leading role in sequential decisions compared to posterior parietal cortex and relies on nonlinear integration of sensory and mnemonic information for decision formation.

β-Hydroxybutyrate accumulates in the perfused rat heart during ischaemia, driven by flux through both HMGCS and SCOT, with implications for functional recovery.