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Page 92 of 1,751
    1. Chromosomes and Gene Expression

    Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity

    Shihui Chen, Carolyn Marie Phillips
    RNA interference pathways are spatially and temporally organized during Caenorhabditis elegans embryogenesis, with the Argonaute protein NRDE-3 playing distinct roles in regulating genes in different cell types and developmental stages.
    1. Microbiology and Infectious Disease

    HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest

    Dhaval Ghone, Edward L Evans ... Aussie Suzuki
    HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.
    1. Cell Biology

    Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome

    Laura Childers, Jieun Park ... Michel Bagnat
    The gut microbiome regulates protein absorption activity in lysosome-rich enterocytes (LREs) and causes broad gene expression changes, while LRE activity also affects the microbiome.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Exploring the repository of de novo-designed bifunctional antimicrobial peptides through deep learning

    Ruihan Dong, Rongrong Liu ... Cheng Zhu
    Peptides designed by artificial intelligence restrict both drug-resistant bacteria and rapidly evolving viruses.
    1. Microbiology and Infectious Disease

    Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis

    Nelson V Simwela, Eleni Jaecklein ... David G Russell
    Prevention of either lipid uptake or lipid catabolism in infected macrophages restricts the ability of Mycobacterium tuberculosis to grow inside these cells.
    1. Neuroscience

    Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs long-term memory by fragmenting sleep

    Lin Yan, Litao Wu ... Chang Liu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning

    Yusuke Sakai, Saumik Sen ... Akihisa Terakita
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Epidemiology and Global Health

    Understanding Pain in Polycystic Ovary Syndrome: Health Risks and Treatment Effectiveness

    Tess Cherlin, Stephanie Mohammed ... Shefali S Verma
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Transcriptional Dynamics Uncover the Role of BNIP3 in Mitophagy during Muscle Remodeling in Drosophila

    Hiroki Taoka, Tadayoshi Murakawa ... Naonobu Fujita
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Representation of male features in the female mouse Accessory Olfactory Bulb, and their stability during the estrus cycle

    Oksana Cohen, Yoram Ben-Shaul
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing