Browse our latest research

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    1. Ecology
    2. Evolutionary Biology

    Lichen mimesis in mid-Mesozoic lacewings

    Hui Fang, Conrad C Labandeira ... Yongjie Wang
    The earliest fossil evidence of a mimetic relationship between the Jurassic moth lacewing Lichenipolystoechotes and its co-occurring fossil lichen Daohugouthallus predates modern lichen-insect associations by 165 million years.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Intra-species differences in population size shape life history and genome evolution

    David Willemsen, Rongfeng Cui ... Dario Riccardo Valenzano
    Population genetics in turquoise killifish wild populations reveals how small population size and genetic drift determine the accumulation of deleterious gene variants leading to short lifespan.
    1. Neuroscience

    Axonal mechanisms mediating γ-aminobutyric acid receptor type A (GABA-A) inhibition of striatal dopamine release

    Paul F Kramer, Emily L Twedell ... Zayd M Khaliq
    GABA-A receptors on dopamine neuron axons not only depolarize the membrane but also limit action potential propagation, an effect potentiated by positive allosteric modulators of GABA-A receptors like diazepam (Valium).
    1. Plant Biology

    KATANIN-dependent mechanical properties of the stigmatic cell wall mediate the pollen tube path in Arabidopsis

    Lucie Riglet, Frédérique Rozier ... Thierry Gaude
    KATANIN1 in stigma papilla cells prevents disordered pollen tube growth and straightens pollen tube direction, allowing the pollen tube to find its correct path to the underlying female tissues.
    1. Genetics and Genomics

    Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

    Melissa A Chiasson, Nathan J Rollins ... Douglas M Fowler
    Human vitamin K epoxide reductase (VKOR) has a four transmembrane domain topology that supports the use of a homology model, enabling identification of active site residues and human variant impact.
    1. Evolutionary Biology

    Behavioural diversity of bonobo prey preference as a potential cultural trait

    Liran Samuni, Franziska Wegdell, Martin Surbeck
    Bonobo groups that share overlapping ranging areas and engage in regular social exchange show "behavioural group identity" of hunting techniques in the absence of local ecological variation.
    1. Structural Biology and Molecular Biophysics

    Slowly folding surface extension in the prototypic avian hepatitis B virus capsid governs stability

    Cihan Makbul, Michael Nassal, Bettina Böttcher
    Duck Hepatitis B core protein forms capsids with a slowly folding extension domain which folding competence is important for viral replication.
    1. Neuroscience

    Amphetamine reduces reward encoding and stabilizes neural dynamics in rat anterior cingulate cortex

    Saeedeh Hashemnia, David R Euston, Aaron J Gruber
    Amphetamine reduces reward signaling by neurons in rat prefrontal cortex, but increases the stability of population dynamics, which account for animals’ increased task engagement, despite reduced reward motivation.
    1. Developmental Biology

    Regulation of dynamic pigment cell states at single-cell resolution

    Margherita Perillo, Nathalie Oulhen ... Gary Wessel
    Multimodal technologies and the experimental tractability of sea urchin embryos reveal diverse regulatory mechanisms and unique genes for distinct pigment cell states.
    1. Medicine
    2. Neuroscience

    Neural signatures of α2-Adrenergic agonist-induced unconsciousness and awakening by antagonist

    Jesus Javier Ballesteros, Jessica Blair Briscoe, Yumiko Ishizawa
    Instant performance recovery is possible following general anesthesia-induced unconsciousness using antagonist, and the brain dynamics return abruptly to the awake state without intermediate recovery states.