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    1. Medicine
    2. Neuroscience

    Parkinson’s Disease: Debunking an old theory

    Teresa Spix, Aryn Gittis
    Recording the neural activity of cells in the brain of patients with Parkinson's disease challenges long-standing assumptions about how this disease manifests at the cellular level.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Mutations: A larger target leads to faster evolution

    Bing Yang, Scott A Rifkin
    The speed at which a cell fate decision in nematode worms evolves is due to the number of genes that control the decision, rather than to a high mutation rate.
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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Seasonal Influenza: The challenges of vaccine strain selection

    Amanda C Perofsky, Martha I Nelson
    New measures of influenza virus fitness could improve vaccine strain selection through more accurate forecasts of the evolution of the virus.
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    1. Structural Biology and Molecular Biophysics

    Membrane Transport: Riding elevators into and out of cells

    Adam W Duster, Hai Lin
    The mechanisms responsible for the trafficking of carboxylate ions across cell membranes are becoming clearer.
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    1. Computational and Systems Biology
    2. Developmental Biology

    Vascular Biology: Severing umbilical ties

    Jessica E Wagenseil, Karen M Downs
    High levels of proteins called proteoglycans in the walls of umbilical arteries enable these arteries to close rapidly after birth and thus prevent blood loss in newborns.
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    1. Computational and Systems Biology
    2. Neuroscience

    Connectomes: Mapping the mind of a fly

    Jason Pipkin
    Scientists have created the most detailed map of the fruit fly brain to date, identifying over 25,000 neurons and 20 million synapses.
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    1. Neuroscience

    Pregnancy Loss: A possible link between olfaction and miscarriage

    Neven Borak, Johannes Kohl
    Unexplained repeated pregnancy loss is associated with an altered perception of male odors and differences in brain regions that process smells.
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    1. Evolutionary Biology

    Adaptation: Evolution of island lizards remains a mystery

    Kathryn D Kavanagh
    Lizards that live in the Greater Antilles exploit a large range of skeletal variations to adapt to similar habitats, in defiance of the theory of plasticity-led evolution.
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Multi-Level Selection: The perils of cheating

    M Florencia Camus
    Experiments on mitochondrial DNA in worms highlight that cheating does not always pay off.
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    1. Genetics and Genomics

    Sexual Reproduction: Reading the epigenetic code for exchanging DNA

    Mathilde Biot, Bernard de Massy
    Three independent studies show that a protein called ZCWPW1 is able to recognize the histone modifications that initiate the recombination of genetic information during meiosis.
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