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    1. Neuroscience

    Memory: A divalent boost from magnesium

    Willem J Laursen, Paul A Garrity
    Enhanced levels of dietary magnesium improve long-term memory in fruit flies.
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    1. Computational and Systems Biology

    Cardiac Optogenetics: A move in the light direction

    Eike M Wülfers, Franziska Schneider-Warme
    Computer simulations show how low-intensity illumination can be used to terminate cardiac arrhythmias.
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    1. Structural Biology and Molecular Biophysics

    Small-Molecule Inhibitors: Disrupting enzyme fluidity

    Ganesh Srinivasan Anand
    A combination of X-ray crystallography, NMR, and mass spectrometry has revealed how diverse small-molecule inhibitors bind Bruton’s tyrosine kinase and alter the conformation of this enzyme.
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    1. Biochemistry and Chemical Biology
    2. Medicine

    Bone Hormones: Survival of the glycosylated

    Harry C Blair, Paul H Schlesinger
    Osteocalcin is a bone matrix protein that acts like a hormone when it reaches the blood, and has different effects in mice and humans.
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    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Enzymes: The two roles of complex III in plants

    Hans-Peter Braun
    Atomic structures of mitochondrial enzyme complexes in plants are shedding light on their multiple functions.
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    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Polygenic Scores: How well can we separate genetics from the environment?

    Jennifer Blanc, Jeremy J Berg
    A simulation study demonstrates a better method for separating genetic effects from environmental effects in genome-wide association studies, but there is still some way to go before this becomes a "solved" problem.
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    1. Neuroscience

    Blood Flow: Supplying the sleeping brain

    Stephanie D Williams, Laura D Lewis
    During sleep, the brain experiences large fluctuations in blood volume and altered coupling between neural and vascular signals.
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    1. Evolutionary Biology

    Telomeres: Change and HOAP for the best

    Claudia Castillo-González, Dorothy E Shippen
    HOAP is a telomere-binding protein that has a conserved role in Drosophila, but it also needs to evolve quickly to restrict telomeric retrotransposons.
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    1. Genetics and Genomics

    Metabolism: Muscle signals to the rescue

    Arely V Diaz, Tânia Reis
    The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Viruses: Neutralizing SARS-CoV-2

    Eric Poeschla
    Experiments with hybrid viruses are illuminating how SARS-CoV-2 can escape neutralizing antibodies.
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