Browse our Insights

Page 2 of 87
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Machine Learning: Lighting up protein design

    Grzegorz Kudla, Marcin Plech
    Using a neural network to predict how green fluorescent proteins respond to genetic mutations illuminates properties that could help design new proteins.
    Insight
    Available as:
    • HTML
    • PDF
    1. Immunology and Inflammation

    Autoimmunity: Redoxing PTPN22 activity

    Magdalena Shumanska, Ivan Bogeski
    The oxidative state of a critical cysteine residue determines the enzymatic activity of a phosphatase involved in T-cell immune responses.
    Insight
    Available as:
    • HTML
    • PDF
    1. Biochemistry and Chemical Biology

    Genetic Code: Expanding codon size

    Tarana Siddika et al.
    Engineering transfer RNAs to read codons consisting of four bases requires changes in tRNA that go beyond the anticodon sequence.
    Insight
    Available as:
    • HTML
    • PDF
    1. Genetics and Genomics
    2. Medicine

    Cancer: The aging epigenome

    Brandon L Pierce
    A new approach helps to assess the impact of accelerated epigenetic aging on the risk of cancer.
    Insight
    Available as:
    • HTML
    • PDF
    1. Neuroscience

    Learning: The devil is in the task structure

    Orit Nafcha, Uri Hertz
    Conflicting evidence about how the brain processes social and individual learning stems from which type of information is presented as the primary source of knowledge during experiments.
    Insight
    Available as:
    • HTML
    • PDF
    1. Neuroscience

    Perception: Where functional MRI stops, metabolism starts

    Polytimi Frangou, William T Clarke
    Combining techniques that track blood oxygenation and biochemicals during neuronal activity reveals how the brain computes perceived and unperceived stimuli.
    Insight
    Available as:
    • HTML
    • PDF
    1. Structural Biology and Molecular Biophysics

    Artificial Intelligence: Exploring the conformational diversity of proteins

    Avner Schlessinger, Massimiliano Bonomi
    An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.
    Insight
    Available as:
    • HTML
    • PDF
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Viruses: A frameshift in time

    Martina M Yordanova, Pavel V Baranov
    The efficiency with which ribosomes shift reading frames when decoding viral RNA may change over the course of an infection.
    Insight
    Available as:
    • HTML
    • PDF
    1. Evolutionary Biology

    Sexual Conflict: Evolving new ways to secure a mate

    Xiaodan Lin, Dong Ren
    Fossils shed light on mating strategies in scorpionflies.
    Insight
    Available as:
    • HTML
    • PDF
    1. Cell Biology

    Cytoskeleton: Capturing intermediate filament networks

    Pierre A Coulombe
    Mapping intermediate filaments in three dimensions reveals that the organization of these filaments differs across cell types.
    Insight
    Available as:
    • HTML
    • PDF