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Receptors: How low can you go?
H Steven Wiley
Extremely low numbers of active epidermal growth factor receptors are sufficient to drive tumor growth.
Developmental Biology and Stem Cells
Patterning and Axis Formation: Heterodimers reign in the embryo
Benjamin Tajer, Mary C Mullins
Experiments by three independent groups on zebrafish have clarified the role of two signaling factors, Nodal and Gdf3, during the early stages of development.
Pollination: Solar flower power
Julia Bing, Danny Kessler
Bumblebees use invisible temperature patterns on flowers to make foraging decisions.
Genomics and Evolutionary Biology
Sex Chromosome Evolution: Culture shock
Antoine Molaro, Harmit S Malik
Many different human cell lines, including both normal and cancer cells, appear to converge to a state that contains an unusual number of chromosomes when they are grown in culture.
Epigenetics: How does obesity lead to insulin resistance?
Chan Hee J Choi, Paul Cohen
Experiments on mice show that an enzyme called DNA methyltransferase 3a is involved in insulin resistance via an epigenetic mechanism.
Intracellular Diffusion: How bacteria keep proteins moving
Conrad W Mullineaux
Bacteria contain large numbers of negatively-charged proteins to avoid the electrostatic interactions with ribosomes that would dramatically reduce protein diffusion.
Epidemiology and Global Health
Plant Pathology: Plasmid-powered evolutionary transitions
Ryan A Melnyk, Cara H Haney
The acquisition of a virulence plasmid is sufficient to turn a beneficial strain of
bacteria into a pathogen.
Computational and Systems Biology
Deep Learning: Branching into brains
Adam Shai, Matthew Evan Larkum
What can artificial intelligence learn from neuroscience, and vice versa?.
Biophysics and Structural Biology
Vesicles: Looking inside the cell
Eric C Arakel, Blanche Schwappach
Advances in imaging techniques have shed new light on the structure of vesicles formed by COPI protein complexes.
Urodynamics: How the brain controls urination
Anna P Malykhina
Coordination between the brainstem and the cortex helps to ensure that urination occurs at an appropriate time.
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