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A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

The buildup of knot-like RNA structures in brain cells may be the key to understanding how uncontrolled protein aggregation drives Alzheimer’s disease.

Proteins that allow water to move in and out of cells help shape the development of new blood vessels.

The ligand Netrin mediates axon guidance through a combination of haptotaxis over short distances and chemotaxis over longer distances.

Nature has inspired the design of improved inhibitors for cancer-causing proteins.

Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

The first complete 3D reconstruction of the compound eye of a minute wasp species sheds light on the nuts and bolts of size reduction.

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.

The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.