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Breast Cancer: Targeting mutant estrogen receptors
Suzanne E Wardell et al.
A drug used in hormone replacement therapy can target estrogen receptors that have become resistant to breast cancer treatments.
Microbiology and Infectious Disease
Physics of Living Systems
Carboxysomes: How bacteria arrange their organelles
The structures responsible for photosynthesis in bacteria use the nucleoid and two unique proteins as a scaffold to position themselves.
Sexual Differentiation: A matter of timing
Michael W Perry, Claude Desplan
A genetic pathway involved in development works together with the sex-determination pathway to control the timing of sexually dimorphic neural development in
Glutamate Receptors: Family matters
Mark L Mayer, Timothy Jegla
Genome sequence data from a range of animal species are raising questions about the origins of glutamate receptors.
Paleobotany: Did flowering plants exist in the Jurassic period?
David Winship Taylor, Hongqi Li
The discovery of a fossil that might be the oldest flowering plant will continue the debate on the origin and structure of ancestral flowering plants.
Memory Formation: Let’s replay
Reactivating brain activity patterns during sleep enhances memory performance the next day.
Human Biology and Medicine
Stem Cells and Regenerative Medicine
Insulin: Folding mutations suppress early beta-cell proliferation
Honey Modi, James D Johnson
Exploring how proliferation and maturation of beta-cells can be impaired after birth will shed light on the origins of various forms of diabetes.
Cancer Immunotherapy: A peptide puzzle
Jian Guan, Nilabh Shastri
Why does cancer develop in situations where the immune system is perfectly capable of eliminating it?
Working Memory: Separating the present and the future
Qing Yu, Bradley R Postle
The brain stores information that is needed immediately and information that will be needed in the future in different ways.
Social Neuroscience: How does social enrichment produce health benefits?
Oxytocin appears to link social interaction and cell aging in rats, especially in females.
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