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Human thalamic activity transformed via thalamocortical functional connectivity to support task representations across functional domains.

Genetic and biochemical analyses reveal that the bacterial nucleases PNPase and RNase R work in concert with a type III-A CRISPR-Cas immune system to process small CRISPR RNAs and ensure robust immunity against foreign nucleic acid invaders.

Structural analysis of the mitoribosomal small subunit with streptomycin reveals the molecular basis for antibiotic binding and new physiological components such as FeS clusters that assemble between mitochondria specific proteins.

Opposing mechanisms determine dendrite arbor size during a critical period in Drosophila.

Cleavage/polyadenylation, the process generating mRNA 3' ends, is linked at the nucleotide level to the position of RNA polymerase II, indicating a spatial coupling so polyadenylation occurs rapidly upon emergence of the nascent RNA from the Pol II elongation complex.

A high-throughput extension of PhIP-seq reveals novel antigen specificities leading to new insights across multiple human autoimmune and inflammatory diseases, enables application of machine learning approaches to PhIP-seq datasets, and highlights the importance of controlled PhIP-seq cohorts.

A novel machine learning approach improves quantitative comparisons of mouse and human brains using spatial transcriptomics data sets.

Investigation of regulatory network topology reveals latent design principles of multistable phenotypic landscape.

Drosophila suzukii, which lays eggs on ripe fruits, differs from Drosophila melanogaster in sweet sensation, mechanosensation, and their integration.

The human entorhinal-hippocampal circuitry is characterized by an information-specific functional organization where two routes, that are preferentially connected to the parahippocampal cortex or the perirhinal and retrosplenial cortices, divide the entorhinal cortex as well as hippocampal subiculum and CA1 subregions.