Deepti Karandur, Moitrayee Bhattacharyya ... John Kuriyan
Activation and autophosphorylation of CaMKII releases the regulatory segment, which can then bind to and destabilize the hub assembly by trapping large fluctuations in the hub architecture.
The terminal selector-type transcription factor UNC-3/Ebf partially modifies the suite of its target genes at different life stages to establish and maintain the identity of C. elegans motor neurons.
Elise Laura Savier, James Dunbar ... Michael Reber
A dominant sensory map provides positional information through correlated activity and transposed molecular cues to guide secondary sensory projections for alignment and organization.
Colin M Cleary, Thiago S Moreira ... Daniel K Mulkey
Understanding how loss of CO2/H+ vascular reactivity affects respiratory control may facilitate development of treatments for breathing problems in this population.
Isabelle Mackrous, Jérome Carriot ... Maurice J Chacron
Whether central vestibular neurons implement faithful stimulus encoding for the vestibulo-occular reflex or optimized coding via temporal whitening for other vestibular functions is determined by neural variability.
Vincent Huson, Marieke Meijer ... Lennart Niels Cornelisse
Modulation of the energy barrier for membrane fusion is a common mechanism by which sensors in the synapse produce supralinear calcium dependence of vesicle release and short-term synaptic potentiation.