Carlos A Ramirez Carbo, Olalekan G Faromiki, Beiyan Nan
A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall and thus transmits proton motive force from the inner membrane to cell surface.
Sphinganine-1-phosphate (SA1P) is linked to paclitaxel-induced peripheral neuropathy, offering a potential target for reducing this severe side effect of paclitaxel treatment.
Cortices from 11 primate species share the same archetypal fractal shape, indicating a universal mechanism for primate and mammalian cortical folding, and suggesting novel shape biomarkers for brains.
Like two peas in a pod but not exactly alike, similar molecules targeting the same bacterial protein behave differently, requiring systems biology and target deconvolution to gain better comprehension.
A calcium transient measurement system utilizing human induced pluripotent stem cell-derived cardiomyocytes reveals the detrimental impact of inflammatory cytokines on cardiomyocyte relaxation and displays the potential of drugs to reverse these defects.
Marcelo A Carignano, Martin Kroeger ... Igal Szleifer
The Self Returning Excluded Volume model is the first heuristic, stochastic chromatin model that reproduce single cell and ensemble based experiments bridging nucleosome and chromosome scales.
For the first time, high-frequency terahertz stimulation is shown to effectively alleviate chronic pain symptoms in mice by regulating neuronal activity in the cortex.
Long-latency reflexes flexibly encode future goals during sequential reaching movements, reflecting the parallel and task-dependent processing of a sequence of goals in circuits that mediate fast feedback control.