Browse our Research Articles

Page 235 of 1,392
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Comparing the evolutionary dynamics of predominant SARS-CoV-2 virus lineages co-circulating in Mexico

    Hugo G Castelán-Sánchez, Luis Delaye ... Marina Escalera Zamudio
    An in-depth exploratory analysis of the evolutionary and epidemiological dynamics of SARS-CoV-2 in Mexico during the first year of the epidemic provides an overview of different virus dynamics between the developing and developed world (represented by the USA and Mexico).
    1. Cell Biology
    2. Immunology and Inflammation

    CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation

    Francesco Andreata, Marc Clément ... Giuseppina Caligiuri
    CD31 plays a pivotal role in neutrophil migration to inflamed sites by localizing to the uropod and promoting effective actin/integrin polarization and detachment, shedding light on the molecular mechanisms underlying extravasation and inflammation response.
    1. Neuroscience

    Novelty and uncertainty differentially drive exploration across development

    Kate Nussenbaum, Rebecca E Martin ... Catherine A Hartley
    From middle childhood to early adulthood, the preference to engage with novel choice options remained consistent, but aversion to reward uncertainty increased.
    1. Cell Biology

    Coalescent RNA-localizing and transcriptional activities of SAM68 modulate adhesion and subendothelial basement membrane assembly

    Zeinab Rekad, Michaël Ruff ... Ellen Van Obberghen-Schilling
    Distinct and direct functions of the RNA binding protein SAM68 regulate integrin signaling and focal adhesion dynamics that condition basement membrane deposition and angiogenic behavior of endothelial cells.
    1. Neuroscience

    Variability of visual field maps in human early extrastriate cortex challenges the canonical model of organization of V2 and V3

    Fernanda Lenita Ribeiro, Ashley York ... Alexander Puckett
    The representation of the retina in early visual cortex shows that human brains have diverse functional organizations, raising questions about developmental mechanisms for visual map formation and how reliably these can be described by average templates.
    1. Cell Biology
    2. Medicine

    Amelioration of non-alcoholic fatty liver disease by targeting adhesion G protein-coupled receptor F1 (Adgrf1)

    Mengyao Wu, Tak-Ho Lo ... Chi-Ming Wong
    The novel role of Adgrf1 in the progression of fatty liver was revealed and targeting Adgrf1 is a promising therapeutic strategy for treating NAFLD patients.
    1. Cancer Biology
    2. Immunology and Inflammation

    Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression

    Kim Bich Nguyen, Malte Roerden ... Stefani Spranger
    In vivo modeling of neoantigen-restricted heterogeneity shows that clonal expression of neoantigens enhances anti-tumor T cell responses by increasing the stimulatory capacity of dendritic cells in the lymph node.
    1. Neuroscience

    Targeted memory reactivation in human REM sleep elicits detectable reactivation

    Mahmoud EA Abdellahi, Anne CM Koopman ... Penelope A Lewis
    Sound cues that were associated with memories during wake elicit memory reactivations when replayed to human participants during rapid eye movement sleep, those memory reactivations are identifiable by machine learning models that directly relate electroencephalography patterns of wake and sleep.
    1. Neuroscience

    No evidence from complementary data sources of a direct glutamatergic projection from the mouse anterior cingulate area to the hippocampal formation

    Lilya Andrianova, Steliana Yanakieva ... Michael T Craig
    A combination of anterograde and retrograde anatomical-tracing methods failed to provide evidence of a recently described projection from the anterior cingulate area to the hippocampus.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions

    Damien Detraux, Marino Caruso ... Patricia Renard
    Accumulation of succinate during the in vitro modeling of embryonic stem cell state transition critically regulate cell fate.