Browse our Research Articles

Page 234 of 1,418
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Vicia faba SV channel VfTPC1 is a hyperexcitable variant of plant vacuole Two Pore Channels

    Jinping Lu, Ingo Dreyer ... Rainer Hedrich
    Polymorphic residues of a vacuolar Ca2+ sensor site in TPC1 channels differ between species of Brassicacea and Fabaceae and lead to distinct TPC1 gating behavior.
    1. Developmental Biology

    Overburdened ferroptotic stress impairs tooth morphogenesis

    Haisheng Wang, Xiaofeng Wang ... Ling Ye
    The accumulation of ferroptotic stress during tooth development has a critical effect on its morphogenesis.
    1. Plant Biology

    Characterization of tryptophan oxidation affecting D1 degradation by FtsH in the photosystem II quality control of chloroplasts

    Yusuke Kato, Hiroshi Kuroda ... Wataru Sakamoto
    Oxidative modification of Tryptophan residues in the reaction center protein D1 may be a key to drive the Photosystem II repair, likely enhancing accessibility of FtsH protease to D1.
    1. Developmental Biology

    Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals

    Merve Bilgic, Quan Wu ... Fumio Matsuzaki
    Single-cell transcriptome analyses during cortical brain development in ferrets and its comparison with public human datasets reveal that there are common progenitors and lineages among gyrencephalic mammalian brain development.
    1. Chromosomes and Gene Expression

    Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase

    Léonard Colin, Celine Reyes ... Sylvie Tournier
    Telomeric proteins Taz1 or Mit1 specifically regulate telomere association of condensin which is essential for sister-telomere disjunction in mitosis by restraining telomere association of cohesin.
    1. Developmental Biology

    Single-cell RNA sequencing unravels the transcriptional network underlying zebrafish retina regeneration

    Laura Celotto, Fabian Rost ... Michael Brand
    Single-cell transcriptome analysis of the regenerating retina in adult zebrafish reveals molecular control steps during Müller glia stem cell activation, progressive differentiation, and neural regeneration.
    1. Neuroscience

    The shared and unique neural correlates of personal semantic, general semantic, and episodic memory

    Annick FN Tanguay, Daniela J Palombo ... Louis Renoult
    Four types of declarative memory rely on different weightings of similar component processes, according to fMRI and subjective ratings.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform

    Enja Tatjana Kipfer, David Hauser ... Thomas Klimkait
    CLEVER enables the rapid manipulation and direct rescue of plus-strand RNA viruses with the shortest hands-on time to study viral variants of concern.
    1. Cancer Biology
    2. Computational and Systems Biology

    Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records

    Jessica Xin Hjaltelin, Sif Ingibergsdóttir Novitski ... Søren Brunak
    A comprehensive comparison of the two types of pancreatic cancer symptom trajectories can in combination leverage a fuller potential of large health data and ultimately aid the detection of early risk factors for pancreatic cancer.
    1. Biochemistry and Chemical Biology

    Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2

    Kehan Chen, Lie Wang ... Gang Wu
    Six-transmembrane epithelial antigen of the prostate isoform 1 (STEAP1) can establish a physiologically relevant electron transfer chain and STEAP2 can transfer electrons via a diffusible FAD mechanism.