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Id2 GABAergic interneurons represent a fourth major group of local inhibitory neurons that includes neurogliaform cells, and these neurons can be targeted using intersectional genetics, revealing their distinctive connectivity and in vivo activity properties.

A computational approach examines the roles of splicing factors and their association with evolutionary change in splicing.

Carefully controlling the level of protein synthesis reduction and mode of translation inhibitor action reveal different and sometimes opposing phenotypic effects following proteostasis stress, wherein protection via initiation inhibition specifically depends on heat shock factor 1.

A new type of mRNAs-loaded CD133⁺ vesicles, named intercellsome, mediate cell-cell communications to compensate intracellular proliferative signal deficit, representing a previously unrecognized mechanism of cell proliferation under stress.

Germline extrachromosomal circular DNAs are mainly formed by microhomology-mediated ligation of nucleosome-protected fragments and barely contribute to de novo genomic deletions at meiotic recombination hotspots.

The absence of DMRT1 induces a male-to-female sex reversal in XY rabbits and complete infertility in both sexes.

Systemic treatment with di-methyl-amino-parthenolide facilitates CNS axon regeneration and functional recovery by reducing the induction of microtubule detyrosination by established regenerative therapies.

Different species-level characteristics and sociocultural factors influence scientific and societal interest in biodiversity, with important implications for species-level conservation and dissemination.

A novel trans-humeral prosthesis control method based on artificial intelligence, and the proof of its effectiveness in virtual reality as well as on a robotic platform.

A subtle mutation in the ATP-binding site of inositol hexakisphosphate kinases increases their conformational flexibility and thereby makes them susceptible to isozyme-selective, allosteric inhibition.