Tylor R Lewis, Sebastien Phan ... Vadim Y Arshavsky
Maturation of light-sensitive 'disc' membranes in vertebrate photoreceptors requires a precise balance between their content of the visual pigment rhodopsin forming the disc body and tetraspanin proteins forming the disc rim.
Consistent with an existing computational model of hippocampal function, using real-time feedback to drive artificial memories at the trough of the hippocampal theta rhythm improves apparent recall.
Lenka Koudelková, Markéta Pelantová ... Daniel Rösel
The functional role of novel regulatory mechanism within prototypic oncogenic kinase c-Src is described with particular emphasis on cancer cell migration, invasiveness, oncogenic transformation, and multilevel regulation of Src itself.
Elizabeth Griggs, Kyle Trageser ... Giulio Maria Pasinetti
New evidence of brain proinflammatory cascades supports post-acute sequelae of SARS-CoV-2 infection, ultimately promoting the onset and progression of Alzheimer's disease as a function of age.
Kai J Sandbrink, Pranav Mamidanna ... Alexander Mathis
To isolate and study proprioception, hierarchical deep neural networks paired with biomechanical models provide a normative approach to test the role of task effects on neural representations, such as the emergence of kinematic tuning and higher-level abstractions of actions.
Pedro Sampaio, Sara Pestana ... Susana Santos Lopes
Zebrafish have a physiological time-window of 1 hr for breaking left-right symmetry and are highly sensitive to the left-right organizer anterior fluid mechanics rather than to the nature of its fluid content.
The yeast syntaxin homolog Tlg2p-residing sub-compartment within the trans-Golgi network is the primary endocytic-accepting region that serves as an early/sorting compartment.
Angelo Ascani, Sara Torstensson ... Elisabet Stener-Victorin
Androgen receptor activation modifies B cell frequencies and functionality, accompanied by weight gain in female mice exposed to human PCOS IgG, highlighting the unrecognized involvement of B cells in PCOS autoimmune comorbidities despite their absence not preventing PCOS phenotype development.
Jackie Kleynhans, Lorenzo Dall'Amico ... SA-S-HTS Group
While recognizing study design limitations, the lack of association between household close range proximity events and SARS-CoV-2 transmission, suggests that aerosol transmission may play a larger role than droplet transmission in the household.
Proteomic analysis in a novel cell-free system for the study of mitophagy, identifies candidate proteins involved in the enforcement of clonal, maternal inheritance of mitochondria and mitochondrial genes in mammals.
