Matias I Autio, Efthymios Motakis ... Roger SY Foo
Depiction of novel human genomic safe harbour loci that have been validated in vitro for safety and stable expression in human embryonic stem cells and cell types from all the three germ lineages.
Rabina Mainali, Nancy Buechler ... Matthew A Quinn
Proteomic-based discovery of a novel mechanism of action affording anti-steatotic properties of itaconate through stabilization of fatty acid oxidation enzyme protein abundance.
Isw1 acts as a master regulator in modulating the expression of drug-resistance genes, and this regulatory mechanism is dependent on the interaction of Isw1 acetylation and ubiquitination.
Nora C Brown, Benjamin Gordon ... Mariana Federica Wolfner
A functional genetics approach reveals a novel role for odorant binding proteins in post-mating processes, with complex mechanisms of evolutionary change across closely related insect species.
Reto B Cola, Diana M Roccaro-Waldmeyer ... Marco R Celio
Foxb1-expressing hypothalamic neurons in the parvafox nucleus and the dorsal premammillary nucleus both contribute to behavioral and physiological components associated with defensive behavior.
Real-time visualization of Salmonella enterica and polarized macrophage interaction in the living host identifies an anti-inflammatory, pro-regenerative, and motionless macrophage subset as a survival niche during persistent infection.