Browse our Research Articles

Page 250 of 1,418
    1. Developmental Biology
    2. Evolutionary Biology

    Hierarchical morphogenesis of swallowtail butterfly wing scale nanostructures

    Kwi Shan Seah, Vinodkumar Saranathan
    Structured illumination microscopy reveals that the hierarchical development of complex honeycomb-like nanostructures within the lumen of some swallowtail butterfly wing scales proceeds via a novel reorganization of disintegrating F-actin bundles.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

    Thiruma V Arumugam, Asfa Alli-Shaik ... Jayantha Gunaratne
    Intermittent fasting orchestrates molecular shifts, yielding cardiovascular improvements, revealing novel cardioprotective mechanisms, and suggesting innovative pharmacological strategies for cardiovascular disease prevention and treatment.
    1. Evolutionary Biology

    Coevolution of the CDCA7-HELLS ICF-related nucleosome remodeling complex and DNA methyltransferases

    Hironori Funabiki, Isabel E Wassing ... Thomas Carroll
    Coevolution analysis suggests that a DNA methylation-related role for the nucleosome remodeling ATPase HELLS and its activator CDCA7 was broadly inherited from the last eukaryotic common ancestor.
    1. Epidemiology and Global Health

    Prediction of diabetic kidney disease risk using machine learning models: A population-based cohort study of Asian adults

    Charumathi Sabanayagam, Feng He ... Ching Yu Cheng
    Integrating machine learning (ML) models with selected features improved the prediction accuracy of diabetic kidney disease compared to traditional logistic regression models using established features, revealing potential new markers and supporting the use of ML techniques in epidemiological studies.
    1. Computational and Systems Biology
    2. Neuroscience

    Dynamic organization of cerebellar climbing fiber response and synchrony in multiple functional components reduces dimensions for reinforcement learning

    Huu Hoang, Shinichiro Tsutsumi ... Keisuke Toyama
    Dimensions for reinforcement learning reduced by dynamic organization of cerebellar climbing fiber response and synchrony in multiple functional components.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growth

    Francesca G Tomasi, Satoshi Kimura ... Matthew K Waldor
    Surveying Mycobacterium tuberculosis tRNA modification leads to identification of a modification promoting Mtb pathogenesis.
    1. Computational and Systems Biology

    A transfer-learning approach to predict antigen immunogenicity and T-cell receptor specificity

    Barbara Bravi, Andrea Di Gioacchino ... Rémi Monasson
    An interpretable machine learning approach can recapitulate the molecular features associated to immune protein-protein binding and leverage them for the prediction of immune response specificity.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Synchronization of oscillatory growth prepares fungal hyphae for fusion

    Valentin Wernet, Marius Kriegler ... Reinhard Fischer
    Fungal hyphae constantly undergo signal oscillations, comparable to a cell 'monologue' until they meet another hypha with which they then coordinate signal oscillations and transit into a cell-to-cell dialogue.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A CRISPR-based rapid DNA repositioning strategy and the early intranuclear life of HSV-1

    Juan Xiang, Chaoyang Fan ... Pei Xu
    An inducible two-component CRISPR-based platform that rapidly repositions HSV-1 genomes to the nuclear edge unveils intranuclear space heterogeneity for the incoming viral genomes and dynamic stages of the host-virus interplay during early infection.
    1. Developmental Biology
    2. Neuroscience

    The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

    Xiong Yang, Rong Wan ... Ke Tang
    Two intrinsic factors converge to govern the differentiation and integration of distinct characteristics of the hippocampus in mice.