Browse our Research Articles

Page 28 of 1,451
    1. Neuroscience

    Balancing safety and efficiency in human decision-making

    Pranav Mahajan, Shuangyi Tong ... Ben Seymour
    A separate fear system, flexibly gated by outcome uncertainty, guides decision-making to be both safe and efficient during exploration.
    1. Neuroscience

    The influence of temporal context on vision over multiple time scales

    Kacie Lee, Reuben Rideaux
    Across multiple scales, temporal context shapes visual perception through an attention-dependent process facilitating rapid motor responses and an attention-independent process suppressing neural encoding of expected events.
    1. Neuroscience

    Patchy striatonigral neurons modulate locomotor vigor in response to environmental valence

    Sarah Hawes, Bo Liang ... Huaibin Cai
    Patchy striatonigral neurons regulate implicit locomotor speed selection based on environmental valence, revealing a subtype-specific mechanism by which striatal circuits shape adaptive motor control and value-dependent behavioral responses.
    1. Neuroscience

    Micro-scale control of oligodendrocyte morphology and myelination by the intellectual disability-linked protein acyltransferase ZDHHC9

    Hey-Kyeong Jeong, Estibaliz Gonzalez-Fernandez ... Gareth M Thomas
    Loss of ZDHHC9, a protein acyltransferase that is highly expressed in oligodendrocytes, does not grossly impact myelination but markedly alters oligodendrocyte morphology and myelination at the micro/nano-scale.
    1. Neuroscience

    Representation of male features in the female mouse accessory olfactory bulb, and their stability during the estrus cycle

    Oksana Cohen, Yoram Ben-Shaul
    Electrophysiological recordings in female mice show that response profiles of accessory olfactory bulb neurons remain stable during the course of the estrus cycle.
    1. Neuroscience

    Nonlinear feedback modulation contributes to the optimization of flexible decision-making

    Xuanyu Wu, Yang Zhou
    Precise feedback connections in posterior parietal cortex enable iterative computation between decision processes, optimizing flexible decision-making reliability.
    1. Physics of Living Systems

    Design principles of transcription factors with intrinsically disordered regions

    Wencheng Ji, Ori Hachmo ... Ariel Amir
    Intrinsically disordered regions in transcription factors enhance both target binding probability and search efficiency.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Telomeres control human telomerase (TERT) expression through non-telomeric TRF2

    Antara Sengupta, Soujanya Vinayagamurthy ... Shantanu Chowdhury
    Telomere length controls hTERT expression by modulating TRF2 distribution and PRC2-mediated repression, highlighting a self-regulatory mechanism in cancer.
    1. Neuroscience

    Sparse innervation and local heterogeneity in the vibrissal corticostriatal projection

    Kenza Amroune, Lorenzo Fontolan ... Ingrid Bureau
    Functional connectivity mapping reveals sparse, specific, and largely complementary cortical innervation of individual striatal medium spiny neurons within overlapping and loosely topographical projections from the barrel cortex.
    1. Neuroscience

    Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing

    Jiho Park, Grayson O Sipe ... Mriganka Sur
    Astrocytic GABA transporter 3 is essential for preserving the integrity of neuronal population dynamics in accurately encoding and representing sensory information.