The substantia nigra inhibits all PPN neurons and causes place aversion, while the globus pallidus selectively inhibits caudal non-cholinergic PPN neurons and causes place preference.
Maria Ardaya, Marie-Catherine Tiveron ... Fabio Cavaliere
A population of ischemia-induced newborn astrocytes, positive for Thbs4, that migrate to the lesion border, where they produce and degrade hyaluronan, modulating the local extracellular matrix, has been identified.
Souleymane Diallo, Kateřina Kašparová ... Robert Hanus
Identification of the trail-following pheromone receptor in the termite Prorhinotermes simplex represents the first functional characterization (deorphanization) of an odorant receptor in termites.
Bing Guo, Shannon Takala-Harrison, Timothy D O'Connor
hmmIBD outperforms alternative tools in detecting genome segments that are identical-by-descent and uncovering signals of positive selection and demographic history in malaria parasite genomes, underscoring the importance of tool prioritization and optimization for reliable malaria genomic surveillance.
Thomas Balligand, Claire Carpenet ... Maarten Dewilde
Two radio-labeled nanobodies and a single knock-in mouse model suffice to track the biodistribution of various unmodified cell-types in live mice by PET/CT.
The cryoEM structure of a RAD51 displacement loop reveals the molecular mechanism of the strand-exchange reaction at the centre of eukaryotic homologous recombination.
Wide-gauge posture in the limb skeleton of Titanosauriformes is an exaptation to gigantism, as it is not correlated with body size in deeply branching titanosaurs.
Rosanna P Sammons, Stefano Masserini ... Dietmar Schmitz
The asymmetric connectivity between thorny and athorny pyramidal neurons in the CA3 region is the key in maintaining the separation of peak firing during sharp wave events.
Population trajectories of premotor cortex mirror neurons progress through distinct subspaces during execution versus observation of reach-grasp-manipulate movements, yet latent dynamics can be aligned, indicating similar relationships among neural representations.
