Browse our Research Articles

Na_V1.2 and Na_V1.6 have unique functional roles in neocortical pyramidal cells, regulating dendritic and axonal excitability, respectively.

PRDM16 directs BMP signaling outcomes by guiding SMAD complex genomic binding to repress neural stem cell proliferation and promote choroid plexus epithelial specification.

S100a4⁺ alveolar macrophages facilitate angiogenesis through CPT1A-PPAR-γ-mediated fatty acid metabolism, thereby triggering atypical adenomatous hyperplasia.

Customized AlphaFold-based modeling of distinct functional states of the hERG channel, a major drug anti-target, significantly improves drug affinity predictions, enhancing cardiac safety screening for arrhythmia risk.

Individuals with borderline personality disorder maintain rigid, distinct self-other representations, disrupting the bidirectional generalisation that underpins adaptive social learning and interpersonal trust.

Polyphosphate, a universal stress response regulator, binds distinctively to different starting ensembles of the same protein leading to either condensates or aggregates that in turn can solubilize or further aggregate, showcasing their ability to finely control the assembly process.

The Drosophila microbiome regulates the cycling of gut metabolites in a circadian clock and diet-dependent manner.

Two lateral striatal subregions integrate the acquisition of stimulus-based decision-making in spatiotemporally and functionally different manners, challenging the prior model through a dominance change from the associative to sensorimotor subregions.

The fine-tuning of mutual inhibition and disinhibition of sleep-regulating neurons and also the memory consolidation that occurs during NREM sleep are controlled by oscillations in serotonin levels.

In methicillin-resistant Staphylococcus aureus, evolution of bacteriophage resistance causes trade-offs that re-sensitize the bacteriato β-lactam antibiotics.